Showing posts with label fatty liver. Show all posts
Showing posts with label fatty liver. Show all posts

Wednesday, 12 November 2025

Enhanced Deep Learning Model for Accurate and Automated Detection of Hepatic Steatosis | Chapter 4 | Mathematics and Computer Science: Research Updates Vol. 8

 

Background: Hepatic Steatosis is one of the most prevalent liver disorders globally. Ultrasound imaging is widely used as the primary screening tool for Hepatic Steatosis. However, its diagnostic performance can vary significantly depending on the operator’s skill and the quality of the equipment. Recent advances in deep learning have brought new opportunities to medical imaging, providing automated, consistent, and quantitative assessments that reduce dependency on operator expertise.

 

Objectives: This study aims to develop a deep learning (DL)-based framework that enhances the detection and grading of Hepatic Steatosis from ultrasound images. The key goal is to achieve accuracy levels comparable to experienced radiologists while maintaining interpretability and efficiency for real-time use in clinical practice.

 

Methods: B-mode ultrasound images and cine clips were collected from patients, covering multiple liver views to capture diverse anatomical perspectives. Alongside imaging data, patient metadata such as age, body mass index (BMI), and comorbid conditions were also recorded to enrich the dataset. The proposed system employs a multi-view ultrasound preprocessing approach, followed by transfer learning to leverage existing feature representations. Attention-driven convolutional neural networks (CNNs) are then used to capture fine details across image regions. To ensure clinical usability, explainability modules are integrated, allowing transparent interpretation of model predictions.

 

Findings: Experimental evaluation demonstrated that the framework outperformed traditional single-view methods, offering improved sensitivity and specificity in detecting hepatic Steatosis. The performance was closely aligned with radiologist-level assessments. Furthermore, the system showed low latency, highlighting its suitability for near-real-time diagnostic applications.

 

Conclusion: Unlike conventional models that rely on a single static image, this study introduces a multi-view fusion strategy enhanced with attention mechanisms and explainability tools. This combination not only strengthens predictive accuracy but also ensures transparency and trustworthiness, critical factors for adoption in clinical settings. Despite the promising performance, challenges such as data variability, subtle early-stage disease patterns, and model interpretability remain. Addressing these limitations through larger, diverse datasets and explainable AI approaches will be essential for translating these models into clinical practice.

 

 

Author(s) Details

A. Sahaya Mercy
Department of Computer Science, St. Joseph’s College (Autonomous), Tiruchirappalli-2, Affiliated to Bharathidasan University, Tamil Nadu, India.

 

G. Arockia Sahaya Sheela
Department of Computer Science, St. Joseph’s College (Autonomous), Tiruchirappalli-2, Affiliated to Bharathidasan University, Tamil Nadu, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/mcsru/v8/6581

Thursday, 26 October 2023

Ionic Detoxification Ameliorates Obesity and Reduces Fatty Liver in Rats Exposed to a High-Fat Diet | Chapter 12 | Advanced Concepts in Medicine and Medical Research Vol. 2

 Ionic complete and sudden withdrawal from an addictive substance (ID) or ionic water soap treatment is considered a natural alternative method to reinforce health, but it currently lacks healthy scientific evidence to support allure efficacy. The theory underlying this study is that consistent ID situation may speed the elimination of toxic fragments from the body and mitigate metabolic disorders, including corpulence. To assess the impact of ID treatment on corpulence and fatty liver inferred by a high-fat diet, male Wistar rats were bear hardship either a low-fat control diet, a high-fat (HF) diet, or a HF diet followed by ID treatment (executed three times per week) over an 11-period period. The study calculated triglyceride levels and examined the verbalization of genes related to fatty acid absorption in both perirenal fatty tissue and the liver. Results showed that rats augment the HF diet exhibited considerably increased material weight, liver weight, and fatty tissue pressure (both perirenal and epididymal) compared to those on the reduced-fat diet. However, the rats subjected to ID situation alongside the HF diet displayed a meaningful reduction in body burden and perirenal adipose fabric weight persuaded by the high-fat diet. Furthermore, ID situation led to a decrease in hepatic cholesterol and triglyceride elements of larger object. Regarding liver function, ID treatment primarily damaged fatty acid absorption. It significantly discounted the expression of genes involved in greasy acid synthesis (in the way that acetyl-CoA carboxylase and fatty acid synthase mRNA) more significantly than those guide fatty acid corrosion (such as carnitine palmitoyl-transferase 1 and acyl CoA oxidase mRNA). This desires that ID treatment may decrease the result of fatty acids in the liver, that could contribute to lower triglyceride levels.

Author(s) Details:

Hsien-Tsung Yao,
Department of Nutrition, China Medical University, 91, Hsueh-Shih Road, Taichung, 404, Taiwan.

Please see the link here: https://stm.bookpi.org/ACMMR-V2/article/view/12287