Showing posts with label hepatic steatosis. Show all posts
Showing posts with label hepatic steatosis. Show all posts

Wednesday, 12 November 2025

Enhanced Deep Learning Model for Accurate and Automated Detection of Hepatic Steatosis | Chapter 4 | Mathematics and Computer Science: Research Updates Vol. 8

 

Background: Hepatic Steatosis is one of the most prevalent liver disorders globally. Ultrasound imaging is widely used as the primary screening tool for Hepatic Steatosis. However, its diagnostic performance can vary significantly depending on the operator’s skill and the quality of the equipment. Recent advances in deep learning have brought new opportunities to medical imaging, providing automated, consistent, and quantitative assessments that reduce dependency on operator expertise.

 

Objectives: This study aims to develop a deep learning (DL)-based framework that enhances the detection and grading of Hepatic Steatosis from ultrasound images. The key goal is to achieve accuracy levels comparable to experienced radiologists while maintaining interpretability and efficiency for real-time use in clinical practice.

 

Methods: B-mode ultrasound images and cine clips were collected from patients, covering multiple liver views to capture diverse anatomical perspectives. Alongside imaging data, patient metadata such as age, body mass index (BMI), and comorbid conditions were also recorded to enrich the dataset. The proposed system employs a multi-view ultrasound preprocessing approach, followed by transfer learning to leverage existing feature representations. Attention-driven convolutional neural networks (CNNs) are then used to capture fine details across image regions. To ensure clinical usability, explainability modules are integrated, allowing transparent interpretation of model predictions.

 

Findings: Experimental evaluation demonstrated that the framework outperformed traditional single-view methods, offering improved sensitivity and specificity in detecting hepatic Steatosis. The performance was closely aligned with radiologist-level assessments. Furthermore, the system showed low latency, highlighting its suitability for near-real-time diagnostic applications.

 

Conclusion: Unlike conventional models that rely on a single static image, this study introduces a multi-view fusion strategy enhanced with attention mechanisms and explainability tools. This combination not only strengthens predictive accuracy but also ensures transparency and trustworthiness, critical factors for adoption in clinical settings. Despite the promising performance, challenges such as data variability, subtle early-stage disease patterns, and model interpretability remain. Addressing these limitations through larger, diverse datasets and explainable AI approaches will be essential for translating these models into clinical practice.

 

 

Author(s) Details

A. Sahaya Mercy
Department of Computer Science, St. Joseph’s College (Autonomous), Tiruchirappalli-2, Affiliated to Bharathidasan University, Tamil Nadu, India.

 

G. Arockia Sahaya Sheela
Department of Computer Science, St. Joseph’s College (Autonomous), Tiruchirappalli-2, Affiliated to Bharathidasan University, Tamil Nadu, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/mcsru/v8/6581

Saturday, 16 October 2021

Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications: An Advanced Study | Chapter 15 | New Visions in Science and Technology Vol. 6

 Fatty liver illness is becoming more common around the world, which has sparked interest in noninvasive liver fat research. MRS (magnetic resonance spectroscopy) is a useful method for detecting metabolites directly in tissue or other areas of interest. In both academic and clinical trials, MRS has been utilised to measure liver fat noninvasively in vivo. MRS has shown outstanding performance in detecting liver fat with high sensitivity and specificity when compared to biopsy and other imaging modalities. MRS is commonly considered as the gold standard for noninvasive liver steatosis detection because to these properties. The purpose of this book chapter is to provide a fast review of the MRS principle and its use for assessing liver fat, as well as a summary of MRS research in contrast to other approaches.

Author (S) Details  

 Duanghathai Pasanta

Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.

Khin Thandar Htun

Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.

Jie Pan

Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand and Shandong Provincial Key Laboratory of Animal Resistant Biology, College of Life Sciences, Shandong Normal University, Jinan 250014, China.

Suchart Kothan

Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.

View Book :- https://stm.bookpi.org/NVST-V6/article/view/4146

Friday, 30 July 2021

Potential Targets for Prevention and Treatment of Nonalcoholic Fatty Liver Disease in Adults: A Review | Chapter 6 | Technological Innovation in Pharmaceutical Research Vol. 8

 NAFLD (nonalcoholic fatty liver disease) is a common illness that can develop to serious liver problems such hepatic fibrosis and hepatocellular cancer. Sedentary behaviour and a high-calorie diet are the most typical causes. There is currently no FDA-approved medicine to treat NAFLD in the United States, leaving only dietary changes, increased physical activity, exercise, and antioxidants as possibilities. The Drug Controller General of India (DGCI) authorised Saroglitazar Mg as a new drug application (NDA) to treat NAFLD in India in December 2020. The pathogenesis, diagnostic procedures, and prospective targets for NAFLD prevention and treatment are all detailed in this review.


Author (s) Details

Jarnail Singh Braich
Department of Pharmacology, Pt BD Sharma Postgraduate Institute of Medical Sciences, Rohtak-124001 (IN), India.

View Book :- https://stm.bookpi.org/TIPR-V8/article/view/2209