Showing posts with label bioactive. Show all posts
Showing posts with label bioactive. Show all posts

Monday, 8 December 2025

A Review on the Phytochemical Composition and Pharmacological Potential of Cissus quadrangularis L. | Chapter 02 | Research Perspective on Biological Science Vol. 9

 

The family Vitaceae consists of several species of plants that have many properties to cure many illnesses and disorders in mankind. Many plant extracts have been reported to have pharmacological uses in many therapies. Manufacturing and pricing of herbal pharmaceuticals can make them more favourable to be exploited in research and progress of new treatment approaches, permitting patients to connect to new medications which are faster and safer for relexification. This review reveals a species of Cissus named Cissus quadragularis L., about its medicinal and herbal uses and its utilisation in the medical field due to the presence of bioactive compounds such as tannin, alkaloid, and flavonoids, as it is used in the drug and cosmetic industry. This review explores the phytochemical composition and pharmacological potential of Cissus quadrangularis, focusing on its application in herbal formulations. The plant exhibits a diverse array of bioactive compounds, including triterpenoids, steroids, flavonoids, and phenolic glycosides, found in various parts such as the stem, leaves, fruits, and roots. These phytochemicals contribute to its broad pharmacological activities, which include anti-ulcer, anti-inflammatory, analgesic, anti-diabetic, antioxidant, antiobesity, anticarcinogenic, antimicrobial, and bone-healing properties, and female health, as it is used to regulate menstruationduet. Although the review shows therapeutic and pharmacological properties and uses of Cissus quadrangularis as a medicinal herb. It was concluded that the root stem leaves, fruit extracts of the plant C. quadrangularis have therapeutic potential and are acknowledged to possess wound healing, antioxidant, and antimicrobial activity and are regularly used to quicken the process of bone fracture healing. The plant is considered a versatile medicinal plant in both the Ayurvedic and modern drug development fields for its valuable therapeutic uses. C. quadrangularis needs to be appraised in scientific research using specific experiments on animal models and clinical trials to recognise the molecular mechanism of action, in the exploration of lead molecules from natural resources.

 

Author(s)details:-

 

Ruchika Khatri
IIS (Deemed to be University), Jaipur, India.

 

Smita Purohit
Department of Botany, IIS (Deemed to be University), Jaipur, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rpbs/v9/6591

Friday, 13 October 2023

Antiplasmodial Potentials and GC-MS Analysis of Bioactive Compounds in Methanol and Ethanol Leaf Extracts of Daniellia oliveri | Chapter 7 | Research Advances in Microbiology and Biotechnology Vol. 7

 The aim of the study was to resolve D. oliveri utilizing qualitative, all-inclusive, and Gas Chromatography-Mass Spectroscopy (GC-MS) analytical systems to screen for phytochemical components and determine bioactive essences. The information concerning phytochemical compounds are not only supportive for finding of therapeutic potential, but also have an alive contribution towards finding of new semi-synthetic and artificial compounds. The identification of bioactive details required for evaluating the antiplasmodial potentials of flammable liquid and ethanol leaf extracts of Daniellia oliveri (D. oliveri) concede possibility be accomplished by subjective, quantitative, and Gas Chromatography-Mass Spectrometry (GC-MS) analyses. The leaves were composed in Anyigba, Kogi state from which intoxicating and ethanol extracts were prepared, phytochemical parts detected and bioactive compounds driven using GC-MS. Results demonstrated the presence of alkaloid, tannin, reducing carbohydrate, saponin, terpenoid, phenol, cardiac glycosides and flavonoid in the extracts. Phenol showed the maximal concentration (46.14 and 43.09 mg/100g) while terpenoid showed hostile concentration (10.63 and 9.97 mg/100g) in intoxicating and ethanol extracts respectively. GC-MS study revealed the closeness of higher elements (57) in methanol extract compared to intoxicating extract (27). This study provides controlled evidence that methanol may be a better ancestry solvent for GC-MS reasoning of D. oliveri leaves meant expected used for the determination of antiplasmodial endeavor than ethanol on account of higher components discovered in methanol extract distinguished to ethanol extract.

Author(s) Details:

Muhammed Muazu,
Pharmacology Laboratory, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Abdulsalami Mohammed Sani,
Department of Biotechnology, Nigerian Defence Academy, PMB 2109, Kaduna, Nigeria.

Karderam Bukar Dikwa,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Deborah Madi Dibal,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Kokori Bajeh Tijani,
Department of Pharmacology, Faculty of Basic Clinical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Junaidu Yahaya,
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Please see the link here: https://stm.bookpi.org/RAMB-V7/article/view/12177

Sunday, 19 December 2021

Recent Advancements on Callus and Cell Suspension Cultures: An Effectual Reserve for the Production of Pharmaceutically Significant Metabolites | Chapter 9 | Current Aspects in Pharmaceutical Research and Development Vol. 6

 Alkaloids, glycosides, flavonoids, volatile oils, tannins, resins, and other phytopharmaceuticals are examples of secondary metabolites of pharmaceutical significance. Because their chemical synthesis is either extremely difficult or economically impractical, the majority of these secondary metabolites are currently isolated from wild or cultivated plants. Although production by callus and cell suspension cultures is a lovely alternative, it has only had limited commercial success because to a lack of understanding of how these metabolites are formed. The current book chapter summarises some of the current progress and investigations carried out by authors for the production of useful bioactive secondary metabolites such as withanolides, bacosides, glychyrhizin, reserpine, ajmalicine, amarogentin, plumbagin, and terpenoids from callus and cell suspension cultures of corresponding plant species. Similarly, a lot of thought has gone into it.


Author(S) Details

Ashok Ahuja
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Manoj Kumar Tripathi
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sushma Tiwari
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Niraj Tripathi
Directorate of Research Services, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Gyanendra Tiwari
Department of Plant Physiology, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Nishi Mishra
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Shashank Bhargav
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sharad Tiwari
Biotechnology Centre, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

View Book:- https://stm.bookpi.org/CAPRD-V6/article/view/5161

Monday, 3 August 2020

Bioactive Ingredients in Germinated Brown Rice and Its Consumption | Chapter 12 | Current Research in Agricultural and Food Science Vol.1

This study was aimed to investigate the content of bioactive ingredients and antioxidant properties of
brown rice and germinated brown rice and evaluate the status of using germinated brown rice of
consumers. The total phenolic content, total flavonoid content and percent DPPH inhibition were
measured at different wavelengths by a 96-well spectrophotometer. The quantitative results of the
germinated brown rice extracts treatments showed the presence of phenolic compounds, flavonoids
and the ability of DPPH to inhibit free radicals. The highest total phenolic content was observed in
GL8 with 1465 μg GAE per gram of dry matter and the lowest treatment was 525 μg GAE per gram of
dry matter. The highest total flavonoid content was found in the GL6 treatment with 193 μg QE per
gram of dry matter and the lowest treatments was 27.95 μg QE per gram of dry matter. The inhibition
percentage for scavenging DPPH radical was highest in the GL10 treatment, being 78.38%. More
than 80% of consumers agreed that germinated brown rice more nutritious, 65% of consumers
reported the positive effect of germinated brown rice in reducing blood sugar after using for 3 months

Author(s) Details

Do Tan Khang
Biotechnology and Development Institute, Can Tho University, Vietnam.

View Book :-
http://bp.bookpi.org/index.php/bpi/catalog/book/221