Showing posts with label anticarcinogenic. Show all posts
Showing posts with label anticarcinogenic. Show all posts

Monday, 8 December 2025

A Review on the Phytochemical Composition and Pharmacological Potential of Cissus quadrangularis L. | Chapter 02 | Research Perspective on Biological Science Vol. 9

 

The family Vitaceae consists of several species of plants that have many properties to cure many illnesses and disorders in mankind. Many plant extracts have been reported to have pharmacological uses in many therapies. Manufacturing and pricing of herbal pharmaceuticals can make them more favourable to be exploited in research and progress of new treatment approaches, permitting patients to connect to new medications which are faster and safer for relexification. This review reveals a species of Cissus named Cissus quadragularis L., about its medicinal and herbal uses and its utilisation in the medical field due to the presence of bioactive compounds such as tannin, alkaloid, and flavonoids, as it is used in the drug and cosmetic industry. This review explores the phytochemical composition and pharmacological potential of Cissus quadrangularis, focusing on its application in herbal formulations. The plant exhibits a diverse array of bioactive compounds, including triterpenoids, steroids, flavonoids, and phenolic glycosides, found in various parts such as the stem, leaves, fruits, and roots. These phytochemicals contribute to its broad pharmacological activities, which include anti-ulcer, anti-inflammatory, analgesic, anti-diabetic, antioxidant, antiobesity, anticarcinogenic, antimicrobial, and bone-healing properties, and female health, as it is used to regulate menstruationduet. Although the review shows therapeutic and pharmacological properties and uses of Cissus quadrangularis as a medicinal herb. It was concluded that the root stem leaves, fruit extracts of the plant C. quadrangularis have therapeutic potential and are acknowledged to possess wound healing, antioxidant, and antimicrobial activity and are regularly used to quicken the process of bone fracture healing. The plant is considered a versatile medicinal plant in both the Ayurvedic and modern drug development fields for its valuable therapeutic uses. C. quadrangularis needs to be appraised in scientific research using specific experiments on animal models and clinical trials to recognise the molecular mechanism of action, in the exploration of lead molecules from natural resources.

 

Author(s)details:-

 

Ruchika Khatri
IIS (Deemed to be University), Jaipur, India.

 

Smita Purohit
Department of Botany, IIS (Deemed to be University), Jaipur, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rpbs/v9/6591

Friday, 18 February 2022

Pharmacotherapeutic Potential of Lawsonia inermis L.: Implications and Future Prospective | Chapter 14 | Current Aspects in Pharmaceutical Research and Development Vol. 8

 Both therapeutic and economic uses have been discovered for henna (Lawsonia inermis). Mehendi is made from the pigment lawsone, which is obtained from this plant. The henna plant contains a large number of secondary metabolites, which provide it medicinal qualities such as anticarcinogenic, antidiabetic, analgesic, immunostimulatory, and many others. This produces a big demand pressure that traditional farming can't provide because of the low multiplication rate. The study's main goals are to develop the plant from the lab to the field, analyse the secondary metabolite content of the plant using multiple assays, and see if in vitro plants have higher secondary metabolic accumulation than in vivo plants. HPLC analysis and comparative transcriptome analysis were performed, followed by KEGG analysis of the pathways, to further validate the findings. Methanol performed the best in the secondary metabolic assessments of all the solvents employed in the study. It was also intriguing to discover that in vitro plants accumulated more secondary metabolites than plants in the wild. The TRAPID platform revealed a substantial difference between the plant transcript sets, indicating that gene families and enzymes contributing to secondary metabolites being more abundant in vitro plants. For tissue culture produced plants, KEGG analysis revealed a vast number of pathways associated to secondary metabolites, such as terpenoids, phenols, and flavonoid production, which can be blamed for the plant's diverse medicinal and commercial qualities. As a result, this research reveals that in vitro henna plants accumulate more secondary metabolites and have a higher multiplication rate than traditional farming. These expanded secondary metabolic pathways can improve the efficiency of in vitro plants for the commercial and pharmaceutical industries, allowing them to be propagated in a stable and controlled environment without exposing the plant to stress, preventing overexploitation.


Author(S) Details

Debapriya Das
Lady Brabourne College, India.

Sayak Ganguli
St. Xavier’s College (Autonomous), India.

Debleena Roy
Lady Brabourne College, India.

View Book:- https://stm.bookpi.org/CAPRD-V8/article/view/5690