Role of Metabolic Engineering in the Synthesis of Plant Secondary Metabolites | Chapter 6 | Innovations in Microbiology and Biotechnology Vol. 5

Metabolic engineering has recently emerged as a promising approach for improving secondary metabolite production. Metabolites are the intermediate products of metabolism, and metabolism is a collection of life-sustaining chemical processes within organisms' cells. Bacteria, archaea, and eukaryotes are bacteria that have been shown to limit practically all of the earth's ecological treasures. Their ability to create secondary metabolites is what distinguishes them. The pharmaceutical, agrochemical, and food sectors are all interested in secondary metabolites since they have a wide spectrum of biological functions. In the industrial, agricultural, pharmaceutical, and allied industries, biotechnology has opened up new opportunities for utilising prospective, efficient, and beneficial microbiomes that produce secondary metabolites. The chapter focuses on various approaches and metabolic engineering to boost secondary metabolite yield and scale-up production of the secondary metabolite of choice. The study's main goals are to differentiate between distinct plant secondary metabolites, their origins, functions, and biotechnological uses, as well as microbial secondary metabolites.

Author (s) Details

Dr. Korrapati Narasimhulu
Department of Biotechnology, National Institute of Technology Warangal, Warangal-506004, Telangana, India

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Recent Advancements on Callus and Cell Suspension Cultures: An Effectual Reserve for the Production of Pharmaceutically Significant Metabolites | Chapter 9 | Current Aspects in Pharmaceutical Research and Development Vol. 6

 Alkaloids, glycosides, flavonoids, volatile oils, tannins, resins, and other phytopharmaceuticals are examples of secondary metabolites of pharmaceutical significance. Because their chemical synthesis is either extremely difficult or economically impractical, the majority of these secondary metabolites are currently isolated from wild or cultivated plants. Although production by callus and cell suspension cultures is a lovely alternative, it has only had limited commercial success because to a lack of understanding of how these metabolites are formed. The current book chapter summarises some of the current progress and investigations carried out by authors for the production of useful bioactive secondary metabolites such as withanolides, bacosides, glychyrhizin, reserpine, ajmalicine, amarogentin, plumbagin, and terpenoids from callus and cell suspension cultures of corresponding plant species. Similarly, a lot of thought has gone into it.

Author(S) Details

Ashok Ahuja
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Manoj Kumar Tripathi
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sushma Tiwari
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Niraj Tripathi
Directorate of Research Services, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Gyanendra Tiwari
Department of Plant Physiology, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Nishi Mishra
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Shashank Bhargav
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sharad Tiwari
Biotechnology Centre, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

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Plant Tissue Culture Techniques for Conservation of Biodiversity of Some Plants Appropriate for Propgation in Degraded and Temperate Areas | Chapter 4 | Current Topics in Agricultural Sciences Vol. 4

 Plant biotechnology is being used as a tool for preserving natural habitats and ensuring their long-term use for ecological balance, as well as developing technologies for growing plants in a variety of cropping systems and on difficult soil, improving state-of-the-art technologies for extracting, characterization, and utilising necessary bioactive components, and generating scientific and clinical data to support the health benefits of botanical medicines. By creating micropropagation techniques, plant tissue culture can be used to rapidly reproduce virus-free planting material in plants suitable for degraded lands and temperate locations. Micropropogation is a time and space-saving approach for producing disease-free and elite viral propagules. In vitro gene bank technology allows for the storage and conservation of germplasm, allowing for the preservation of vegetatively propagated plants in cryogene banks and the storage of recalcitrant seeds, embryos, and pollens in liquid nitrogen for lengthy periods of time. This chapter covers micropropagation protocols established in our lab for a variety of plants appropriate for cultivation in undulated areas and temperate climates, as well as the detection and manufacture of natural substances found in plants and ex situ conservation techniques. Biotechnology and high-value plant biodiversity can be combined as a developmental challenge and an economic opportunity in the future.

Author(S) Details

Manoj Kumar Tripathi
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sushma Tiwari
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Niraj Tripathi
Directorate of Research Services, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Gyanendra Tiwari
Department of Plant Physiology, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

Deepa Bhatt
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Megha Vibhute
Krishi Vigyan Kendra, Burhanpur, India.

Neha Gupta
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Nishi Mishra
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Prerana Parihar
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Purnima Singh
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Akash Sharma
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Ashok Ahuja
Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.

Sharad Tiwari
Biotechnology Centre, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

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