Tuesday, 12 July 2022

Determination of Microcytic Hypochromic Anemia (MCHC) for Hemoglobin Variants and Hemoglobinopathies by Using High Performance Liquid Chromatography (HPLC) | Chapter 1 | Challenges and Advances in Pharmaceutical Research Vol. 4

The current study was conducted because anaemia is the most prevalent and often treated clinical condition. It is addressed by a variety of nutritional supplements with little effort put into determining the underlying cause or checking haemoglobin for abnormalities.

Microcytic hypochromic anaemia (MCHC), also known as low cell volume anaemia, is a morphological form of anaemia that clinicians meet in current practise. It has a number of underlying etiologies.

The underlying causes of iron deficiency anaemia include beta thalassemia trait, hemoglobinopathies brought on by Hb E, Hb D, and Hb C, among others. Therefore, we must first check haemoglobin for abnormalities and aberrant hemoglobins before starting therapy.

The Pathology Department of JNMC in Sawangi (Meghe), Wardha, carried out an observational (prospective and retrospective) investigation. One hundred patients' blood samples will be analysed using the High Performance Liquid Chromatography Bio-Rad version to check for different haemoglobin patterns and the hemoglobinopathies connected to them.

To establish their importance and conclusions, the observations will be made in line with the objectives, totaled, and then put through statistical tests.

The data from the protocol research will be used to inform the conclusion.

Author (s) Details:

Kaustubh Vilasrao Kharche,
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, 442004, India.

Arvind Bhake,
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, 442004, India.

Please see the link here:
https://stm.bookpi.org/CAPR-V4/article/view/7503

No comments:

Post a Comment