Regarding sophisticated treatment planning, cancer imaging, and treatment methods, oncology has achieved significant advancements in recent years. Molecular imaging, which enables identifying or describing living biological processes at the cellular and molecular level and is specifically addressed to reveal abnormalities in cells and molecules which cause the cancer, was developed as a result of the limitations of conventional imaging in radiation oncology. The techniques employed include optical imaging, ultrasonography, radiotracer imaging such as PET scan and SPECT, MRI, and MR spectroscopy. Better results can potentially be determined in the early stages by molecular imaging, which enables early diagnosis of cancer cells and prompt treatment. Cell metabolism and proliferation, hypoxia, apoptosis, and angiogenesis are some of the areas where this approach can be used. In the past ten years, molecular imaging-based diagnostic techniques have advanced in the areas of cancer diagnosis and staging, target definition, and response evaluation. The most used imaging method is an 18-FDG PET-CT scan, which is extremely valuable in detecting malignancies of the lung, breast, prostate, lymphoma, and many other types with higher sensitivity and specificity. The development of multimodality treatment approaches that include surgery, radiotherapy, chemotherapy, and molecularly targeted anti-cancer drugs is a result of improvements in our understanding of the pathophysiology of cancer. It can be concluded that using molecular imaging in conjunction with various therapy methods can be very beneficial for the management of cancer.
Author (s) Details
Sheeba Bhardwaj
Department of Radiation Oncology, Pandit BD
Sharma PGIMS, Rohtak, Haryana, India.
Diptajit Paul
Department of Radiation Oncology, Pandit BD
Sharma PGIMS, Rohtak, Haryana, India.
Vivek Kaushal
Department of Radiation Oncology, Pandit BD
Sharma PGIMS, Rohtak, Haryana, India.
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