Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The colder parts of the body, such as the skin and peripheral nerves, are predominantly affected. Leprosy affects the body's biochemical and immunological systems, as well as trace metals such as zinc, copper, and magnesium. After iron, zinc is the second most prevalent trace metal in the body. The goal of this study was to investigate into the amount of serum zinc in leprosy patients and to correlate with clinical manifestations wherever possible. The study comprised 63 persons who had recently been diagnosed with leprosy. After that, the cases were split into clinical subgroups and compared to the controls. Serum zinc levels were evaluated using serum samples collected from venous blood. The majority of patients (26.9%) had Intermediate Leprosy, with Histoid Leprosy being the minority (1.58%). The lowest serum zinc levels were found in pure tuberculoid and indeterminate leprosy patients, whereas the highest were found in pure lepromatous and Erythema nodosum leprosum patients, demonstrating that leprosy patients with higher bacterial burdens had lower serum zinc levels. There may be a link between serum zinc levels and bacillary load, based on this.
Author (s) Details
Pramila Jain
Department of Pathology Gandhi Medical College, Bhopal M.P 462001, India.
Vivek Khare
Department of Pathology Gandhi Medical College, Bhopal M.P 462001, India
Ashish Koshti
Department of Pathology Gandhi Medical College, Bhopal M.P 462001, India.
Reeni Malik
Department of Pathology Gandhi Medical College, Bhopal M.P 462001, India.
Bhawna Bhimte
Department of Medical Biochemistry Gandhi Medical College, Bhopal MP 462001, India.
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