Friday, 20 August 2021

Clinical Profile and Outcomes of Acute Kidney Injury Patients in an Intensive Care Unit in India: A Retrospective Study | Chapter 17 | New Frontiers in Medicine and Medical Research Vol. 1

 Background: Epidemiology and outcome data on acute renal damage are scarce in underdeveloped countries (AKI). By attempting to identify the presenting symptoms, etiologies, treatment methods, and disease prognosis in patients admitted to intensive care units at a tertiary care institution in Mangalore, India, the current single-site study aims to define the clinical profile of AKI in patients admitted to intensive care units.


Between October 2001 and October 2003, 70 AKI patients with serum creatinine levels greater than 1.4 mg/dl and blood urea levels greater than 53 mg/dl were enrolled in this retrospective study at Wenlock district hospital in Mangalore, KMC hospital in Attawar, Mangalore, and KMC hospital in Jyothi circle in Mangalore.

Results: Of the enrolled patients, 45.7 percent were between the ages of 40 and 60, with 49 males and no significant gender difference (p=0.412). Reduced micturition was the most prevalent presenting symptom, which was present in 47.1 percent of patients, and sepsis was the most common aetiology of AKI, which was also related with the greatest fatality rate (17.1 percent). Patients who got conservative treatment (n=52) had a mortality rate of 42.8 percent, while those who had hemodialysis (n=18) had a mortality rate of 4.2 percent. The study's overall survival rate was 52.9 percent.

Conclusions: The epidemiological data in this study is consistent with previous studies in India, with hemodialysis appearing to be more effective than conservative therapy in terms of illness outcomes.

Author (s) Details

Vivek S. Narayan Pillai
Department of Cardiology, Government Medical College, Kannur, Kerala, India.

C. Joe Verghese
Department of Medicine, KMC, Mangalore, Karnataka, India.

Christopher C. Pais
Department of Medicine, KMC, Mangalore, Karnataka, India.

Vijay Gopal Rai
Department of Medicine, KMC, Mangalore, Karnataka, India.

Mahabala Chakrapani
Department of Medicine, KMC, Mangalore, Karnataka, India.

View Book :- https://stm.bookpi.org/NFMMR-V1/article/view/2796

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