With
the toggle switch paradigm, the role of biochemical parameters (such as the
rate constant of repressor expression) in determining the type of stability for
altering gene regulation in Escherichia coli is well established. The
resilience of the system improves with higher order cooperativity of promoter
repression, which helps to achieve bistability in the event of weaker
promoters. The histogram depicts the abrupt transition from a low to a high
level. Two methodologies have been used to investigate the release of protein
concentration with time. The effect of noise is investigated, and it is
discovered that noise varies with system size. The level of noise is also
measured.
Author(s) Details
Sarojini Naidu College for Women. Kolkata. India.
View Book :- https://stm.bookpi.org/NUPSR-V13/article/view/2919
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