Nanoparticles in Dentistry: Applications and Future Perspectives | Chapter 14 | Medical Science: Recent Advances and Applications Vol. 11

Nanoparticles have emerged as a transformative innovation in dentistry, offering unique physicochemical properties that enhance diagnostic, preventive, and therapeutic outcomes. Their high surface-to-volume ratio, antimicrobial activity, and ability to interact at the molecular level have enabled wide-ranging applications across restorative dentistry, endodontics, periodontics, implantology, and oral medicine. Silver, zinc oxide, titanium dioxide, and calcium phosphate nanoparticles have shown promise in combating oral biofilms, preventing secondary caries, improving adhesion in restorative materials, and enhancing remineralisation of dental tissues. In implantology, nanoparticle coatings contribute to osseointegration and infection resistance, while in periodontics, nanocarriers facilitate targeted drug delivery and regenerative therapies. Despite these advances, challenges remain regarding biocompatibility, long-term stability, controlled release, and potential toxicity. Future research is expected to focus on smart nanoparticle systems with stimuli-responsive behaviours, multifunctional composites, and personalised nanodentistry tailored to individual patient needs. Overall, nanoparticles hold significant potential to revolutionize dental practice, improving both clinical efficacy and patient outcomes.

 

 

Author(s) Details

Ioana Stanciu
Department of Physical Chemistry, Faculty of Chemistry, University of Bucharest, 4-12 Elisabeta Blvd, 030018, Bucharest, Romania

 

 

Please see the book here :- https://doi.org/10.9734/bpi/msraa/v11/6349

 

From Macro to Micro: The Rise of Nanoparticles in Endodontics | chapter 10 | Medical Science: Recent Advances and Applications Vol. 10

 

Nanotechnology has emerged as a transformative approach in endodontics, offering innovative strategies to overcome limitations of conventional therapies. Nanoparticles—ultrafine materials sized between 1 and 100 nm—exhibit unique physicochemical and biological properties that enhance antimicrobial efficacy, bioactivity, and mechanical performance of dental materials. This review comprehensively explores diverse nanoparticles, including hydroxyapatite, titanium dioxide, graphene, chitosan, carbon nanotubes, bioactive glass, silver, and copper nanoparticles, detailing their mechanisms of action, clinical applications, and potential in endodontics. These nanomaterials demonstrate capabilities such as biofilm disruption, reactive oxygen species generation, dentinal tubule occlusion, remineralisation, mechanical reinforcement, and regenerative support. Despite their promising therapeutic potential, challenges remain regarding cytotoxicity, stability, controlled release, cost, and regulatory approval. Addressing these barriers through rigorous research and clinical trials may pave the way for nanoparticle-based interventions to become integral components of predictable, long-lasting endodontic treatment outcomes. This review provides a valuable reference for researchers and clinicians seeking to integrate nanotechnology into more effective endodontic treatments.

 

 

Author(s) Details

V. Arun Kalyan
SRM Kattankulathur Dental College and Hospital, Tamil Nadu, India.

 

Tripuravaram Vinay Kumar Reddy
Department of Conservative Dentistry and Endodontics, SRM Kattankulathur Dental College and Hospital, Tamil Nadu, India.

 

Vijay Venkatesh
Department of Conservative Dentistry and Endodontics, SRM Kattankulathur Dental College and Hospital, Tamil Nadu, India.

 

Seetha Kunhikannan
ICON, CRO Chennai, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/msraa/v10/6227

Effect of Nano Selenium-enriched Diet on the Growth Performance and Biochemical Parameters of Labeo rohita | Chapter 9 | Research Perspective on Biological Science Vol. 6

 

Selenium (Se) is an essential microelement utilised in aqua-feeds for aquatic animals’ normal growth, well-being and health. When selenium is present in adequate concentrations in fish diets, protecting against oxidative damage. Selenium is required for the function of several significant seleno-proteins, including glutathione peroxidase (GPx) responses of fish. This study was intended to assess the growth performance of Labeo rohita (Rohu) resulting from the nano Se-merged diet. Nano Se was synthesized and its physico-chemical characteristics were characterized using UV-VIS, SEM, EDAX, XRD and FTIR for varying quantities of nano Se; Diets - I-0, II- 0.5, III-1, IV-1.5, V-2 and VI- 2.5 mg/ kg were prepared, making use of fish meal (FM), groundnut oil cake (GNOC), wheat flour (WF) and tapioca flour (TF). Rohu fingerlings (2 ± 0.5 g) were acclimated for 2 weeks and stocked in triplicate to evaluate growth performance and biochemical parameters under experimental feeding conditions. Feed-utilising parameters and the biochemical composition of Rohu were evaluated subsequently after 28 days. Data on growth parameters were analysed using IBM SPSS software 17. The UV-Vis Spectroscopy revealed that nano Se was assessed in wavelengths of 200 to 500 nm and exhibited strong absorption at 322 nm. The SEM image showed spherical morphology with an average particle diameter of 12.22 μm. EDAX spectrum recorded two signals at 1.5 keV and 11 keV. XRD patterns showed crystalline characteristics of nano Se at 2θ correlators of 23.5o, 29.7o, 41.4o, 43.6o, 45.4o, 51.7o, 55.9o and 61.5o. FTIR spectrum was examined in the range of 4000 – 500 cm-1. Rohu's growth performance and biochemical analysis revealed that the protein, carbohydrate and lipids of gill, liver and muscle of Rohu were highly increased in the case of diet IV containing 1.5 mg/kg nano Se. The study concluded that a fish diet containing 1.5 mg/kg of nano Se is the recommended level for Rohu's effective growth and biochemical criteria.

 

 

Author(s) Details

 

M. Dayana Senthamarai
Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, TN, India.

 

M. Rekha
Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, TN, India.

 

M. R. Rajan
Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, TN, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rpbs/v6/6115

The Cohesive Forces in Explaining Material Phenomena | Chapter 7 | Chemical and Materials Sciences: Developments and Innovations Vol. 9

 

The study of cohesive forces, which fundamentally govern the interaction and integrity of materials, has led to an improved understanding of macroscopic and microscopic phenomena. This manuscript explores cohesive forces as a unifying principle in materials, focusing on their role in organic and inorganic systems. By studying carbon-based materials, it demonstrates how cohesive forces influence structural stability, conductivity and material behavior under diverse conditions. Key findings include the pivotal role of carbon in enhancing material properties and its transformative applications in energy storage systems, graphene-based technologies and protein stability. These insights drive innovations in nanotechnology, biotechnology and sustainable materials.

 

Author(s) Details

 

Rajasekaran Ekambaram
V.S.B. Engineering College, Karudayampalayam, Karur - 639111, TN, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/cmsdi/v9/4132

Stem Cells in Neurocancerology: The Case of Teratocarcinoma and Glioblastoma | Chapter 9 | Medical Science: Recent Advances and Applications Vol. 8

 

Background: Neural stem cell research is a promising field when considering brain disease and glioblastoma therapy. Efficient strategies for glioblastoma treatment were established targeting oncoproteins or growth factors (i.e. IGF-I, AFP) present during embryonic and fetal development of nervous system tissues originating from neural stem cells.

 

Methodology and Results: In a preclinical experiment, the PCC4 stem cells (derived from teratocarcinoma), which give rise to neoplastic neural cells, were transfected in vitro with the anti-IGF-I vectors (antisense and triple helix approaches). This strategy completely hindered the synthesis of the IGF-I and converted the stem cells into immunogenic cells (expressing MHC-I and B7), inducing an in vivo anti-tumour effect. This strategy was successfully applied to glioblastoma therapy. The anti-IGF-I strategy was recently combined with nanotechnology. The application of nanotechnology in stem cell research is based on the use of nanoparticles (NP) for targeted therapeutics, including gene therapies. NP (i.e. theranostic iron oxide) and IGF-I target related signal transduction pathways that lead to cancer cell apoptosis. Other studies have demonstrated that NP loaded with chemotherapy selectively killed cancer stem cells while sparing normal cells.

 

Conclusion: Stem cell- and immunotherapies, including anti-IGF-I gene therapy combined with nanotechnology targeting glioblastoma, are in permanent progress.

 

Author(s) Details

Maryam Raja
Department of Biotechnology, University of Isfahan, 81746-73441 Isfahan, Iran.

Silvia J. Bueno
Faculty of Health Sciences, UNAB University, 681001 Floridablanca, Colombia.

 

Annabelle Trojan
CEDEA & ICGT (Center of Oncology Diagnostic and International Cancer Gene Therapy Foundation), 110010 Bogotá D.C., Colombia and INSERM UMR 1197, Cancer Center & University of Paris / Saclay, 94802 Villejuif, France. 

 

Gabriela Quintero

Faculty of Health Sciences, UNAB University, 681001 Floridablanca, Colombia and CEDEA & ICGT (Center of Oncology Diagnostic and International Cancer Gene Therapy Foundation), 110010 Bogotá D.C., Colombia.

 

Andres Christian
Hospital Bretonneau, University of Tours, 37000 Tours, France.

 

Hebert O. Siachoque
CEDEA & ICGT (Center of Oncology Diagnostic and International Cancer Gene Therapy Foundation), 110010 Bogotá D.C., Colombia.

 

Yu-Chun Lone
INSERM UMR 1197, Cancer Center & University of Paris / Saclay, 94802 Villejuif, France.

 

Alvaro Alvarez
Faculty of Medicine, University of Cartagena, 130001 Cartagena de Indias, Colombia.

 

Jerzy Trojan
CEDEA & ICGT (Center of Oncology Diagnostic and International Cancer Gene Therapy Foundation), 110010 Bogotá D.C., Colombia, INSERM UMR 1197, Cancer Center & University of Paris / Saclay, 94802 Villejuif, France and National Academy of Medicine - ANM, 75272 Paris, France.

 

Please see the book here:- https://doi.org/10.9734/bpi/msraa/v8/5843

Nanotechnology Advances in the Detection and Treatment of Cancer | Chapter 9 | Disease and Health Research: New Insights Vol. 8

Cancer is a life-threatening disease due to which more than ten million people worldwide lose their lives per year. Cancer has many different causes, and prognostic information varies from patient to patient due to the unique molecular characteristics of the human body. However, genetic variability caused by different cancer types and neoplastic alterations makes diagnosis and treatment challenging. Since targeted drug delivery helps patients receive medication by gradually raising drug concentrations in specific body regions, it is regarded as a crucial component of precision medicine in the treatment of cancer. Nanoparticles (NPs) mediated drug delivery can improve local drug delivery systems. Diagnostic tests using NPs enable the identification of biomarkers that accumulate at specific cancer sites, ensuring precise drug delivery planning. However, Nanoparticles can cause immunological reactions and toxicities such as anemia, neutropenia, thrombosis, and allergic reactions. The main purpose of this study is to emphasize the role of nanotechnology in developing novel formulations for cancer treatment.

 

Author (s) Details

Kanika Miglani
Department of Biotechnology, Indira Gandhi University, Meerpur, Rewari, India.

 

Lalit Kumar
Department of Environmental Sciences, Indira Gandhi University, Meerpur, Rewari, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrni/v8/2270

Nanotеchnology-based Solutions for Bеta-thalassеmia: Unravelling Curcumin as a Promising Therapeutic Agent | Chapter 1 | Medical Science: Recent Advances and Applications Vol. 4

 

Background: Beta thalassemia is a blood disorder that affects the production of hеmoglobin, thе protein responsible for transporting oxygen throughout the body. It is caused by a mutation in thе gеnе that controls the production of hеmoglobin bеta globin chains. Beta thalassemia is a group of inherited blood disorders characterised by decreased Hb production, which leads to anaemia, and the body does not have healthy RBCs. Individuals need regular blood transfusions. Thus, transfusions frequently result in side effects, including iron toxicity. A polyphenol called curcumin has anti-inflammatory effects and can raise the body's level of antioxidants. The use of nanocurcumin has shown a better treatment option for beta-thalassemia conditions.

Objective: To evaluate the better treatment option for beta thalassеmia using nano curcumin as a therapeutic tool.

Methods: A comprehensive search to identify the relevant studies was conducted in online databases, mainly Google Scholar, PubMed, Embase, and Scopus. Around 100 articles were identified, and after the title and abstract review, 23 students were included in the review. A literature search was conducted to gather information on beta-thalassemia, nanotechnology, and curcumin. Peer-reviewed articles, scientific journals, and relevant databases were utilised to identify relevant studies and research findings. The search was focused on studies that investigated the application of nanotechnology in beta-thalassemia management and the potential benefits of curcumin in this context.

Results: Nanotechnology offers promising strategies for beta-thalassemia management, enhancing drug delivery and gene therapy. Curcumin, with its antioxidant and anti-inflammatory properties, is being explored for beta-thalassemia but faces bioavailability challenges. Strategies like nanoformulations are being investigated for curcumin's delivery.

Conclusion: Nanotеchnology-based diagnostics, including non-sensory and nano-biosensors, hold promise for еarly detection and monitoring of bеta-thalassеmia. Curcumin mitigatе oxidative strеss, rеducе inflammation, and potеntially allеviatе thе damagе to bеta-thalamic RBCs. Howеvеr, thе bioavailability of curcumin rеmains a challеngе, and stratеgiеs to еnhancе its dеlivеry and stability nееd to bе invеstigatеd.

 

Author (s) Details

Rahul. E
Acharya Institute of Allied Health Sciences, Bengaluru, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/msraa/v4/4756

Advancements in Bulletproof Vest Technology: A Comprehensive Review of Materials, Design, and Applications | Chapter 3 | Science and Technology: Developments and Applications Vol. 10

This review paper examines the evolution, materials, and technological advancements in bulletproof vests, a critical component of protective clothing. Bulletproof vests have been developed to safeguard individuals, primarily in military, law enforcement, and civilian sectors, against ballistic threats. The paper explores the key materials used in bulletproof vests, such as aramid fibers, polyethylene, and advanced composite materials, and analyzes the improvements in design and comfort. Additionally, the paper discusses the regulatory standards, challenges in development, and future directions for enhancing the effectiveness and usability of bulletproof vests. It is designed to safeguard individuals from ballistic threats. This paper provides a comprehensive review of bulletproof vest materials, their technological advancements, and their diverse applications in law enforcement, military, and civilian use. The study examines the evolution of bulletproof vests, analyzing the impact of high-performance fibers such as aramid-based Kevlar and Twaron, as well as Dyneema, which is an ultra-high-molecular-weight polyethylene fiber. The review also explores recent developments in nanotechnology, graphene-based materials, and liquid armor. Additionally, the paper discusses the ergonomic and environmental considerations in vest design, offering insights into future trends in protective clothing. The research also explores legal and regulatory frameworks governing the development and distribution of bulletproof vests, ensuring compliance with global safety standards.

 

Author (s) Details

 

Krishnaveni Vasudevan
Department of Fashion Technology, Kumaraguru College of Technology, Coimbatore – 641049, Tamil Nadu, India.

 

Kavya.D
Department of Fashion Technology, Kumaraguru College of Technology, Coimbatore – 641049, Tamil Nadu, India.

 

Devipriya.V
Department of Management Studies, KSR College of Engineering, Tiruchengode – 637214, Tamil Nadu, India.

Please see the book here:- https://doi.org/10.9734/bpi/stda/v10/5154

Nanotechnology: Applications in Medicine and Beyond | Chapter 8 | Recent Developments in Chemistry and Biochemistry Research Vol. 8

Nanotechnology is the manipulation of materials at the nanoscale, which ranges from 1 to 100 nanometres and has advanced applications in industries such as biology, electronics, transportation, energy, agriculture, cosmetics, space exploration, and environmental research. Nanotechnology in medicine allows for early illness detection, prevention, diagnosis, tailored therapy, and monitoring. Some notable uses include gold nanoparticles as biosensors for genetic sequencing, carbon nanotubes for cancer diagnosis, and nanoparticles in stem cell research. Nanotechnology is integrated into genetic analysis via the use of nanoparticles in atomic force microscopy and quantum dot fluorescence in situ hybridisation. Furthermore, nanoparticles improve polymerase chain reaction (PCR) procedures and function as contrast agents in imaging modalities like ultrasound and MRI. Beyond healthcare, this technology has a transformational influence on contemporary society. Improved nutrient delivery and stress tolerance in crops are among its agricultural advantages, as are food safety, quality, and nutrient bioavailability in the food business. Nanotechnology development has the possibility of addressing major global concerns while also improving quality of life and promoting sustainability.

 

Author (s) Details

John Kiran J
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, India.

 

Kiran Dahiya
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, India.

 

Chordiya Pratiksha Deepak
Department of Periodontology, Pt. BD Sharma PGIDS, Rohtak, India.

 

Urvashi
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, India.

 

Rutul Patel
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, India.

 

Chandini Dash
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, India.

Avi Mittal
Pt. BD Sharma PGIMS, Rohtak, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rdcbr/v8/3229

Applications of Green Chemistry and Nanotechnology as a Potential Solution for Sustainability | Chapter 8 | Recent Developments in Chemistry and Biochemistry Research Vol. 10

Nanotechnology is a crucial tool for the environmentally friendly synthesis of noble nanomaterials. Green synthesis is superior to traditional chemical processes due to its cost-effectiveness, reduced pollution, and enhanced environmental and public health benefits. Nanomaterials, derived from plants, offer numerous benefits to living things. Additionally, nanomaterials are cost-effective, and have minimal environmental and health impacts, making them a promising area of nanotechnologies. This study explores the integration of green chemistry and nanotechnology as a potential solution for sustainable development in the context of global environmental awareness. This study also discusses the integration of various domains and the potential of innovative nanomaterials and methodologies to enhance green chemistry principles. Utilizing nanotechnology can lead to the formation of more cost-effective, environmentally friendly, and sustainable chemical processes. This research shows recent advancements in green synthesis techniques, nanocatalysis, and the utilization of nanomaterials for energy storage and environmental remediation. It emphasizes balancing sustainability by considering nanotechnology's potential risks and lifetime implications. The study explores the green synthesis of nanomaterials, highlighting their benefits in reducing harmful compounds, energy consumption, and process effectiveness. It highlights nanostructured materials for renewable energy, environmental monitoring sensors, and cleaner chemical reactions. It emphasizes the need for risk evaluations and lifecycle analysis for responsible innovation and sustainable practices. This study's findings highlight the necessity of comprehensive regulatory bases and ongoing interdisciplinary research to optimize emerging technologies' economic and environmental benefits. Integrating nanotechnology and green chemistry is crucial to a more sustainable future. This review explores the eco-friendly synthesis of plant-based nanoparticles and their applications in catalysis, drug development, diagnostics, and biological research.

 

 

Author (s) Details

 

Selvaraja Elumalai
Raffles University, Neermanda, India.

 

Meenakshi Sharma
Raffles University, Neermanda, India.

 

Venkata Lakshamana Sagar Dantinapalli
Raffles University, Neermanda, India.

 

Mylsamy Palanisamy
Acharya Nagarjuna University, India.

 

Akhilesh Kumar Kuril
Bhagwant University, Sikar Road, Ajmer, Rajasthan, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rdcbr/v10/3857

Nanoparticles: Characteristics, Preparation, Applications and Challenges in Modern Technologies | Chapter 4| Pharmaceutical Science: New Insights and Developments Vol. 3

Nanoparticles have distinctive characteristics such as their particle size ranges from 1-1000 nm and exhibit special physical, chemical and biological properties and have become a future-proof technology. It has broad effects on a number of sectors including consumer goods, energy and medicine. This overview offers a thorough analysis of the many kinds of nanoparticles, such as polymeric nanoparticles, solid lipid nanoparticles, metallic nanoparticles, etc., as well as methods for preparing and assessing them. The advantages of nanoparticles include increased solubility, targeted drug delivery, enhanced bioavailability and many more. There are many applications of nanoparticles in many fields such as diagnostics, therapeutics, imaging and biosensing. However, there are even demerits of these as potential toxicity, immunogenicity, environmental impacts and even cost is also pretty high. Some of the demerits can be overcome by careful assessment of the manufacturing technique. Furthermore, necessary evaluation techniques can be considered for characterizing the size, shape, surface area and other significant characteristics of nanoparticles.

 

Author (s) Details

Saravanakumar Kasimedu
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Usha Priya Halapaka Selvam
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Keerthishree Suresh Sharma
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Navina Sreenivasan Arrivur
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Nagaveni Pommala
S.V.U. College of Pharmaceutical Sciences, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502, India.

Niranjan Babu Mudduluru
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Mallikarjuna Gandla
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Prudhvi Raj Vadamala
Seven Hills College of Pharmacy (Autonomous), Tirupati, Andhra Pradesh 517561, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/psnid/v3/4293

Application of Nanotechnology for Water Treatment | Book Publisher International

Water contamination is a growing global concern, necessitating advanced treatment strategies to ensure clean and safe water. Nanotechnology offers promising solutions by providing the unique properties of nanomaterials to enhance water purification efficiency. This book explores fundamental aspects of nanomaterials, including metal nanoparticles, metal oxide nanoparticles, carbon-based nanomaterials, and nanocomposites, along with their synthesis and functionalization by using top-down and bottom-up approaches. Key topics include adsorption mechanisms, photocatalysis, and membrane-based technologies for removing heavy metals, organic pollutants, pathogens, and emerging contaminants. The improved efficiency, effectiveness, and flexibility of nano-enabled water treatment are highlighted by compared to traditional approaches. The book also addresses economic feasibility, environmental impact, regulatory considerations, and public acceptance of nanotechnology-driven solutions. Public perception and acceptance of nanotechnology-based solutions are analyzed to assess scalability and real-world implementation. The book concludes with an overview of existing challenges such as nanoparticle stability, regeneration, and safe disposal while outlining future trends in nano-enabled water treatment, including hybrid nanomaterial systems, bio-inspired nanotechnologies, and AI-driven optimization. This book aims to solve current challenges and provide next-generation treatment options for global water security by expanding nanotechnology applications and supporting sustainable water purification techniques.

 

Author (s) Details

 

Dr. Bikram Keshari Das
Nano Innovation Laboratory, School of IKST, Kalinga Institute of Social Sciences (KISS) Deemed to be University, Bhubaneswar-751024, Odisha, India.

 

Dr. Tanushree Das
Nano Innovation Laboratory, School of IKST, Kalinga Institute of Social Sciences (KISS) Deemed to be University, Bhubaneswar-751024, Odisha, India.

 

Miss Surekha Majhi
Nano Innovation Laboratory, School of IKST, Kalinga Institute of Social Sciences (KISS) Deemed to be University, Bhubaneswar-751024, Odisha, India.

 

Mrs. Dipteerekha Das
Nano Innovation Laboratory, School of IKST, Kalinga Institute of Social Sciences (KISS) Deemed to be University, Bhubaneswar-751024, Odisha, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49238-63-3

Precision Engineering in Healthcare: Advanced Drug Delivery, Diagnostics, and Therapeutics through Nanotechnology | Chapter 6 | Exploration of Knowledge and Information in Sciences

 Nanotechnology, which includes the manipulation of matter at 1-100 nanometers, has emerged as a revolutionary field that is determined to transform healthcare. By allowing unprecedented precision engineering, it provides unique opportunities to interact with biological systems at various levels. This helps the system of advanced drug delivery where nanoparticles encapsulate and accurately transport the important medicines to target sites, efficacy enhancement and side effects reduction. Some particular examples include specific treatments for infectious diseases, cancer and neurodegenerative disorders. Additionally, nanomaterials provide the development of imaging agents that are ultrasensitive and biosensors for early detection of disease, as well as engineering artificial tissues for regenerative medicine. Nanotechnology also plays a main role in personalized medicine by increasing accuracy in treatments based on molecular and genetic profiles, conquering antimicrobial resistance and increasing implant integration. Realizing the complete structural role of nanotechnology in healthcare requires ongoing research, collaboration, and attention to regulatory considerations. In summary, nanotechnology signifies a paradigm shift in healthcare, offering innovative approaches to address pressing medical challenges and elevate patient care." Realizing the full potential of nanotechnology in healthcare requires ongoing research, collaboration, and attention to regulatory considerations. In summary, nanotechnology signifies a paradigm shift in healthcare, offering innovative approaches to address pressing medical challenges and elevate patient care."

 

Author (s) Details

Ripu Daman
Department of Biotechnology, Chaudhary Bansi Lal University, Bhiwani-127031, Haryana, India.

 

Monika Miglani
Department of Biotechnology, Chaudhary Bansi Lal University, Bhiwani-127031, Haryana, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-48859-02-0/CH6

Lung Cancer: Exploring Symptoms, Types and Novel Drug Delivery Systems for Treatment | Chapter 11 | Medical Research and Its Applications Vol. 7

Lung cancer reveals itself in a variety of ways, but it is still one of the most common and fatal cancers in the world. This review article discusses the many categories, symptoms, and conventional treatment options for lung cancer in great depth. Lung cancer comes in many histological variants, like non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), each with distinct characteristics and treatment modalities. Significant efforts have been made recently to create innovative medication delivery methods that will maximize therapeutic benefits while reducing adverse outcomes from lung cancer treatment. These cutting-edge strategies include polymer-based carriers, liposomal formulations, and nanoparticle-based drug delivery techniques. These innovative drug delivery systems have the potential to enhance treatment outcomes and quality of life for patients by accurately delivering therapeutic drugs to the tumor site and reducing interactions with healthy tissues. Recent developments regarding the administration of medications for the treatment of lung cancer are highlighted in this review, assessing the effectiveness and safety of innovative formulations.

 

Author (s) Details

Vitthal Chopade
PES’S Modern College of Pharmacy, Yamuna Nagar, Nigdi, Pune-44, Maharashtra, India.

 

Pradnya Waman
PES’S Modern College of Pharmacy, Yamuna Nagar, Nigdi, Pune-44, Maharashtra, India.

 

Shivani Morkhade
PES’S Modern College of Pharmacy, Yamuna Nagar, Nigdi, Pune-44, Maharashtra, India.

 

Hemant Bhoi
PES’S Modern College of Pharmacy, Yamuna Nagar, Nigdi, Pune-44, Maharashtra, India.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/mria/v7/658

Overview on Nanoparticle Classes, Design and Perspectives | Chapter 5 | Innovations in Science and Technology: Shaping a Sustainable Future (Vol. 1)

"Nanotechnology" refers to a broad range of scientific disciplines, including energy storage, chemistry, surface phenomenon, molecular studies, semiconductor science, engineering, microfabrication, and molecular engineering. Particulate systems such as nanoparticles have been employed as a physical means of modifying and enhancing the pharmacokinetic and pharmacodynamic characteristics of several kinds of medicinal compounds. Nanoparticles are applied in vivo to safeguard the drug entity in the bloodstream, limit the drug's access to certain locations, and administer the medication to the site of action at a steady and regulated rate. Enhanced performance above their parent material and flexible nature make nanoparticles (NPs) significantly important in the advancement of technology. Numerous methods, including the dispersion of premade polymers, the polymerization of monomers, and the ionic gelation or co-acerbation of water-based polymers, were used to generate nanoparticles. In this chapter, various methods of synthesis of nanoparticles, their characterizing techniques and important applications are discussed.

 

Author(s)details:-

 

Dr. Rajni Mohil
Department of Chemistry, Government College Nalwa (Hisar), Haryana, India.

 

Dr. Nitya Kaushik
Chemistry Department, MLN College, Yamuna Nagar, Haryana, India.

 

Please See the book here :- https://doi.org/10.9734/bpi/mono/978-81-973809-6-9/CH5

Innovations of Nanotechnology in Various Fields for a Better Future | Chapter 2 | Innovations in Science and Technology: Shaping a Sustainable Future (Vol. 1)

 In the world of modern technologies nanotechnology is developing rapidly. It was first introduced by Richard P. Feynman in his lecture at the California Institute of Technology in 1959. Nanotechnology deals with material sizes ranging between 1-100 nanometers. In our day-to-day life, nanotechnology is already present from textiles to food packaging and transportation Lightweight roads, sea, air, and space vehicles are also the creation of nanotechnology. Nanotechnology and materials also support our health and well-being through wearable biosensors and biomaterials for regenerative medicine like enhancing methods for detection and treatment of diseases like cancer. Nanotechnology-based diagnosis and treatment, nanoparticle-based imaging, and encapsulation of drugs in nanoparticles have led to better drug delivery systems and the use of those encapsulated drugs in nanoparticles in targeted therapies are the most well-known health-related applications.

In upcoming times nanotechnology will have a remarkable contribution to economic growth and job creation. The digital transformation will be accelerated by nanotechnology, which offers a wide range of nano-devices for application in the future of society, including smart robots, driverless cars, and Internet of Things sensors. Making water free from pollutants, reducing CO2 (carbon dioxide) emissions, and solar cells, are some of the contributions of nanotechnology to sustainable society. Nanotechnology is now focusing on manufacturing green nano-products and their utilization to help maintain sustainability and reduce the risk of nano-products to the environment and human health. The future approach of nanotechnology includes food Nanotechnology, Nanodentistry, Nanorobotics, Energy production, and storage with the help of nanotechnology.

 

Author(s)details:-

 

Simran Jolly
Department of Chemistry, DAV University, Jalandhar, India.

 

Sharanjeet Kaur
Department of Chemistry, DAV University, Jalandhar, India.

 

Dr. Shelly Garg
Department of Mathematics, DAV University, Jalandhar, India.

 

Please See the book here :- https://doi.org/10.9734/bpi/mono/978-81-973809-6-9/CH2

Precancerous Disease Systemic Lupus Erythematosus–The Role of BAFF in Corticosteroids Treatment | Chapter 11 | Medical Research and Its Applications Vol. 6

Background: The B cell Activating Factor (BAFF) is implicated as a key cytokine in autoimmune precancerous disease Systemic Lupus Erythematosus, SLE. The objective of the work was to determine how glucocorticoids (GCs) treatment applied in SLE patients affects serum BAFF levels. The described study is the first one to consider this therapeutical internship.                                                                        

Methodology: The study was performed in two groups: 1 - GCs treatment (21 patients); 2 - conventional treatment (8 patients). The first group was divided into three subgroups, according to the dose of GCs: <10.0 mg/day, 10.0-49.0 mg/day and ≥50.0 mg/day). The BAFF measurement in blood was done using the ELISA method. Data were analyzed with descriptive statistical techniques, depending on the type of variable, and the Mann-Whitney inference test.

Results: BAFF values were higher in patients with GCs ≥ 50.0 mg/day, with a mean of 2,844 pg/ml ± 1,495. In patients receiving GCs <50.0 mg/day, the mean was 2,422 ± 1,280. The mean BAFF in patients receiving GCs was 2,482 pg/ml and in the control group 0.990 pg/ml. The difference between these two averages is statistically significant, using the non-parametric Mann-Whitney test, with p <0.001. GCs therapy is associated with an increase in serum BAFF levels using higher doses of GCs. 

Conclusion: The evaluation of serum BAFF level in SLE treatment has become the potential new biomarker of GCs therapy. The presented results constitute a novel contribution to the diagnosis and therapy of SLE.

 

Author(s)details:-

 

Jerzy Trojan
CEDEA / ICGT – Oncological & Autoimmune Diseases Center, Bogota D.C., Colombia and Cancer Center - INSERM & Paris / Saclay University, Villejuif, France.

 

Maryam Raja
CEDEA / ICGT – Oncological & Autoimmune Diseases Center, Bogota D.C., Colombia and  Department of Biotechnology, Isfahan University, Isfahan, Iran.

 

Jose J. Siachoque
CEDEA / ICGT – Oncological & Autoimmune Diseases Center, Bogota D.C., Colombia.

 

Gabriela Quintero
CEDEA / ICGT – Oncological & Autoimmune Diseases Center, Bogota D.C., Colombia and Faculty of Medicine, UNAB University, Floridablanca, Colombia.

 

Alvaro Alvarez
Faculty of Medicine, University of Cartagena, Cartagena de Indias, Colombia.

 

Heber O. Siachoque
CEDEA / ICGT – Oncological & Autoimmune Diseases Center, Bogota D.C., Colombia and Faculty of Science, National University, Bogota D.C., Colombia.

 

Please See the book here :- https://doi.org/10.9734/bpi/mria/v6/7520C

Outlooking the Future with Nanosciences and Nanotechnology and Their Applications | Chapter 9 | Contemporary Perspective on Science, Technology and Research Vol. 7

The small world of matter is getting smaller and smaller. Nano sciences in recent years had huge developments allowing nanotechnologies to take enormous steps in the development of materials and processes. Numerous applications in a wide scope of fields are very beneficial for humans, and much research in development is very promising. Applications in medicine, industry, electronics, energy, or aeronautics are only some examples of areas where enormous benefits exist, and potentialities are clear. Some nanotechnologies are already applied, and others are in development or testing phases.

Author(s) Details:

José António Filipe,
Department of Mathematics, ISTA—School of Technology and Architecture, University Institute of Lisboa (ISCTE-IUL), Information Sciences, Technologies and Architecture Research Center (ISTAR-IUL), Avenida das Forças Armadas, 1649-026 Lisboa, Portugal.

Manuel Alberto M. Ferreira,
Department of Mathematics, ISTA—School of Technology and Architecture, University Institute of Lisboa (ISCTE-IUL), Information Sciences, Technologies and Architecture Research Center (ISTAR-IUL), Avenida das Forças Armadas, 1649-026 Lisboa, Portugal.

Please see the link here: https://stm.bookpi.org/CPSTR-V7/article/view/13746

A Review on Nanotechnology and Nanorobotics: A Miraculous And emerging Tool in Nanomedicine | Chapter 5 | Advanced Concepts in Pharmaceutical Research Vol. 6

Nanotechnology, is the combination of recently developed scientific technology and modified engineering that focuses on production, design and application of a system at an atomic or molecular level. It helps in creating machines or robots by theoretical engineering near about nanometer scale is called “Nanorobotics”. These are named like ‘nanorobots’, ‘nanoids’, ‘nanites/nanomites’ ‘Industrial robots’, ‘humanoid’, ‘surgical robots’ etc. In this article focused on concept, types, working, pharmaceutical approaches, design, advantages, disadvantages, application and future aspects through robotic projects on nanomedicine delivering agent nanorobots in different fields. The development of design of nanorobots has been done by using various approaches such as: Biochip, Nubots, Positional Nano assembly, Usage of Bacteria etc. These are implemented by using several components such as sensors, actuators, control, power, communication and by interfacing cross- special scales between organic inorganic systems. Due to specific site operation mechanism leads no any harmful activities and no side effects in applications. The initial cost of design development is high but accurate delivery of medicine to target site is the boon to mankind. These nano devices are used for the purpose of maintaining and protecting the human body against pathogens in different areas (food, industry, agriculture, farming, space technology etc.). It is helpful in the treatment of cancer (In Obese Prostate Cancer, colon cancer, Kidney cancer etc.), cerebral Aneurysm, removal of kidney stones, Gene therapy, Nano dentistry, Neurosurgery, Diagnosis and Testing, Diamond nanotechnology for skin treatments, implementation of Anti–HIV etc. Various new developed pharmaceutical science-based nanotechnology in various fields of biotechnology, biomaterials synthesis, drug delivery, in diagnosis and treatment monitoring using medical imaging, etc. showed great potential in the field of Nanomedicine. The use of nanorobotic with nanotechnology could become the boon to mankind and a miraculous emerging tool in future nano era.

Author(s) Details:

Gita Chaurasia,
Siddhant College of Pharmacy, Pune, Maharashtra, India.

Please see the link here: https://stm.bookpi.org/ACPR-V6/article/view/13415

Composite Wave Sheets from Basalt Fiber for Pitched Roofing | Chapter 2 | Research and Developments in Engineering Research Vol. 3

 This item describes scientific research on the invention of highly adept asbestos-free composite sheet cover materials established basalt fibers using nanotechnology and creative developments, established local conditions. Since in modern environments the problems of environmentally intimate and durable materials are severe, the authors propose an creative method of replacing resistant to burning and chrysotile fibers in the production of gestured roofing sheets. New ideas and results of exploratory developments, concerning details regulations and practical experiments in this place are proposed. The Mega Invest Industrial joint venture is a complicated basalt fiber builder in Central Asia and the second largest builder in the CIS, which produces a wide range of extreme-strong volcano matter fibers. The authors made an attempt to realize the plan of using local volcano matter fiber for the production of gesturing roofing sheets.

Author(s) Details:

N. F. Bakhriev,
Department of Construction Materials, Samarkand State Architectural and Civil Engineering Institute (SSACEI), Uzbekistan.

N. R. Qurolova,
Department of Construction Materials, Samarkand State Architectural and Civil Engineering Institute (SSACEI), Uzbekistan.

Please see the link here: https://stm.bookpi.org/RADER-V3/article/view/10506