Nanotechnology has emerged as a transformative approach in
endodontics, offering innovative strategies to overcome limitations of
conventional therapies. Nanoparticles—ultrafine materials sized between 1 and
100 nm—exhibit unique physicochemical and biological properties that enhance
antimicrobial efficacy, bioactivity, and mechanical performance of dental
materials. This review comprehensively explores diverse nanoparticles,
including hydroxyapatite, titanium dioxide, graphene, chitosan, carbon
nanotubes, bioactive glass, silver, and copper nanoparticles, detailing their
mechanisms of action, clinical applications, and potential in endodontics.
These nanomaterials demonstrate capabilities such as biofilm disruption,
reactive oxygen species generation, dentinal tubule occlusion,
remineralisation, mechanical reinforcement, and regenerative support. Despite
their promising therapeutic potential, challenges remain regarding
cytotoxicity, stability, controlled release, cost, and regulatory approval.
Addressing these barriers through rigorous research and clinical trials may
pave the way for nanoparticle-based interventions to become integral components
of predictable, long-lasting endodontic treatment outcomes. This review
provides a valuable reference for researchers and clinicians seeking to
integrate nanotechnology into more effective endodontic treatments.
Author(s) Details
V. Arun Kalyan
SRM Kattankulathur Dental College and Hospital, Tamil Nadu, India.
Tripuravaram Vinay
Kumar Reddy
Department of Conservative Dentistry and Endodontics, SRM Kattankulathur
Dental College and Hospital, Tamil Nadu, India.
Vijay Venkatesh
Department of Conservative Dentistry and Endodontics, SRM Kattankulathur
Dental College and Hospital, Tamil Nadu, India.
Seetha Kunhikannan
ICON, CRO Chennai, India.
Please see the book here :- https://doi.org/10.9734/bpi/msraa/v10/6227
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