Thursday, 18 September 2025

Regional Variations in Cancer Burden in Uganda: Insights from Population-based Registries and Implications for National Control Programmes | Chapter 8 | An Overview of Disease and Health Research Vol. 5

 

In Uganda and generally in Sub-Saharan Africa, there is an epidemiologic transition to noncommunicable diseases from infectious diseases. Effective strategies to mitigate the cancer burden may be designed by understanding the underlying factors responsible for this increase in noncommunicable diseases. The cancer registration coverage is low and evenly distributed in all regions of Uganda. This narrative review was conducted to determine the cancer burden in Uganda in order to allow for a timely intervention to mitigate cancer risk factors by Public Health authorities. The primary purpose of the study is to explore the sub-regional cancer spectrum in Uganda among both males and females. This review reveals the low levels of cancer awareness, which contribute to poor cancer screening and therefore present a barrier to cancer control and prevention in this population. In Uganda, there had been a 16% increase in cancer deaths between 2012 and 2018. The most common types of cancers are mainly due to infections, such as those caused by human herpes virus 8, Epstein-Barr virus and human papilloma virus. The sub-regional cancer spectrum in Uganda includes prostate, oesophageal, gastric, liver cancers and Kaposi sarcoma in males. Whilst in females, the sub-regional spectrum includes ovarian, breast, oesophageal and Kaposi sarcoma. Population-based cancer registries in the Central and Northern regions have reported ovarian cancer among the top five most common cancers. There is a significant variation in cancer profile in some sub-regions of Uganda, where non-Hodgkin lymphoma was replaced by gastric cancer in males. This finding reinforces the need to support and establish more population-based cancer registries to encourage the establishment of regional cancer centres, determine the cancer burden and guide national control programmes in the country. Part of the national cancer control programme should include cancer surveillance using population-based cancer registries.

 

Author(s) Details

Richard Wismayer
Department of Surgery, Masaka Regional Referral Hospital, Masaka, Uganda, Department of Surgery, Faculty of Health Sciences, Equator University of Science and Technology, Masaka, Uganda and Department of Surgery, Faculty of Health Sciences, Habib Medical School, IUIU University, Kampala, Uganda.

 

Please see the book here :- https://doi.org/10.9734/bpi/aodhr/v5/6135

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