Water-Based Synthesis of 2-Hydrazinobenzothiazoles: An Improved Approach | Chapter 4 | Chemical and Materials Sciences: Research Findings Vol. 5

 

A novel, eco-friendly synthesis of 2-hydrazinylbenzo[d]thiazoles via the reaction of benzo[d]thiazol-2-amines with hydrazine hydrate in water under reflux has been reported in this book chapter. This method demonstrates broad substrate scope, accommodating various electron-donating and withdrawing groups, and efficiently yields the corresponding 2-hydrazinobenzothiazole derivatives. The aqueous-based approach highlights the method's potential for green chemistry, making it an appealing strategy for synthesising diverse heterocycles such as hydrazones, pyrazoles, pyrazolines, triazoles, and others.

 

 

Author(s) Details

Karan Singh
Department of Chemistry, Indira Gandhi University, Meerpur, Rewari-122502, Haryana, India.

 

Manish Kumar
Department of Chemistry, Indira Gandhi University, Meerpur, Rewari-122502, Haryana, India.

 

Nehal Sagwal
Department of Chemistry, Indira Gandhi University, Meerpur, Rewari-122502, Haryana, India.

 

Kiran
Department of Chemistry, Indira Gandhi University, Meerpur, Rewari-122502, Haryana, India.

 

Sunil Kumar
Department of Physics, Indira Gandhi University, Meerpur, Rewari-122502, Haryana, India.

 

Please see the book here : https://doi.org/10.9734/bpi/cmsrf/v5/6251