Overview on Nanoparticle Classes, Design and Perspectives | Chapter 5 | Innovations in Science and Technology: Shaping a Sustainable Future (Vol. 1)

"Nanotechnology" refers to a broad range of scientific disciplines, including energy storage, chemistry, surface phenomenon, molecular studies, semiconductor science, engineering, microfabrication, and molecular engineering. Particulate systems such as nanoparticles have been employed as a physical means of modifying and enhancing the pharmacokinetic and pharmacodynamic characteristics of several kinds of medicinal compounds. Nanoparticles are applied in vivo to safeguard the drug entity in the bloodstream, limit the drug's access to certain locations, and administer the medication to the site of action at a steady and regulated rate. Enhanced performance above their parent material and flexible nature make nanoparticles (NPs) significantly important in the advancement of technology. Numerous methods, including the dispersion of premade polymers, the polymerization of monomers, and the ionic gelation or co-acerbation of water-based polymers, were used to generate nanoparticles. In this chapter, various methods of synthesis of nanoparticles, their characterizing techniques and important applications are discussed.

 

Author(s)details:-

 

Dr. Rajni Mohil
Department of Chemistry, Government College Nalwa (Hisar), Haryana, India.

 

Dr. Nitya Kaushik
Chemistry Department, MLN College, Yamuna Nagar, Haryana, India.

 

Please See the book here :- https://doi.org/10.9734/bpi/mono/978-81-973809-6-9/CH5

Determining the Effect of Natural Antibiotics on Selected Clinical Isolates from Minna General Hospital, Niger State, Nigeria | Chapter 4 | Pharmaceutical Research - Recent Advances and Trends Vol. 2

 

The present study highlights the effect of Redeemer's Natural antibiotics on selected clinical isolates from Minna General Hospital, Niger State, Nigeria. The knowledge of herbal medicine has grown. In modern times, a wide range of herbs have been sought for their healing effects and are used more and more, while the resort to black magic has been in steady decline. The antimicrobial activity of Redeemer’s Natural antibiotic was tested against five clinical isolates from Minna General Hospital, Niger State (Salmonella typhi, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans), using tube dilution techniques. It was found that Salmonella typhi was markedly affected by the herbal drug at a concentration of 2mg/ml, while Pseudomonas aeruginosa and Escherichia coli were also affected at a concentration of 3mg/ml, all three organisms were inhibited with a zone of inhibition ranging from 5.0mm-14.0mm, while the herbal drug showed no effect on Staphylococcus aureus and Candida albicans. The study further stated that the ethanol leaf and root extract of aloe vera gel has the intended effect of antibacterial activity against both Gram-positive and as well as Gram-negative bacteria. This investigation further assures that the plant extracts could be used for the treatment of microbial infections.  The inactivity of the herbal drug on Staphylococcus aureus and Candida albicans can be due to drug resistance development. There is a promising future for “Redeemer’s Natural Antibiotic” as there are about half a million plants around the world, and most of them are not investigated yet for their medical activities and their hidden potential medical activities could be decisive in the treatment of present and future studies.

 

Author(s)details:-

 

Erena Nuhu Bako
Niger State College of Education Minna, Niger State, Nigeria.

 

Please See the book here :-  https://doi.org/10.9734/bpi/prrat/v2/547

Application of Natural Polymers as Excipients in Dosage Forms | Chapter 8 | Novel Aspects on Pharmaceutical Research Vol. 8

The review focuses on the polymers of unrefined origin and their win importance. Natural polymers, which maybe found in two together woody and non-woodlike plant components such as bark, sources, sap, roots, rhizomes, products, leaves, and plant gums, are typically polymeric polysaccharides. Natural polymers are widely utilised, have less adverse effects, are referring to practices or policies that do not negatively affect the environment, increase bioavailability, are inexpensive, are effortlessly available, and maybe used in a variety of portion of drug or other consumable forms. The paper focuses on an overview of everyday polymers, their characteristics, synthetic components, and applications as excipients in portion of drug or other consumable forms. Natural polymers have also significance in controlled and sustained release studies. The non injurious nature of these everyday products is favorable and classified and mentioned.

Author(s) Details:

A. V. S. Rajeswari,
Department of Pharmaceutics, Joginpally B.R. Pharmacy College, JNTUH, Bhaskar Nagar, Yenkapally, Moinabad, Telangana, India.

P. Sailaja,
Department of Pharmaceutics, Andhra University College of Pharmaceutical Sciences, South Campus, Visakhapatnam, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/NAPR-V8/article/view/11655

Determining the Effects of Immutonic Capsule on CD4T-Lymphocytes Cells Count: A Case Report | Chapter 01 | Innovations in Microbiology and Biotechnology Vol. 3

 Introduction: Many herbs and natural food items have long been thought to be effective panaceas capable of establishing a balanced inflammatory response, encouraging a healthy immunological response, as well as having antibacterial and viral properties. Some drugs have substantial negative effects when used in therapeutic settings. We hypothesised that natural substances may be used as a food supplement, immunological tonic, and antibacterial and viral agent, resulting in a more effective preventative and therapeutic approach to COVID-19 and other illnesses. The goal of the study was to see how the IMMUTONIC capsule affected the number of CD4T lymphocytes in the body.

Presentation of a Case: For one week, a 52-year-old Yemeni female volunteer who was otherwise healthy took three Immutonic capsules after each meal. According to medical histories and physical examinations, she had no substantial cardiac, hepatic, renal, pulmonary, gastrointestinal, neurological, or haematological problems. Before and after taking the IMMUTONIC capsule, blood CD4 T-Lymphocytes cells were analysed.

Conclusion: The current instance shows that Immutonic capsule boosts and enhances the immune system, making it a better preventative, immunity booster, and therapeutic against COVID-19 and other infections.

Author(S) Details

Hussien O. Kadi
Sana’a University, Faculty of Medicine and Health Sciences, Sana’a, Yemen.

H. K. Mohamed
48 Model Hospital, Sana’a, Yemen.

H. K. Taha
Hodiedah University, Faculty of Clinical Pharmacy, Hodiedah, Yemen.

View Book:- https://stm.bookpi.org/IMB-V3/article/view/5353

Effects of Immutonic Capsule in Human Volunteers with Flu Symptoms: A Clinical Approach | Chapter 11 | Recent Developments in Medicine and Medical Research Vol. 13

 Introduction: Historically, many herbs and natural dietary materials have been regarded as powerful panaceas capable of establishing a balanced inflammatory response, fostering a healthy immunological response, as well as having antibacterial and viral properties. Some drugs have substantial negative effects when used in therapeutic settings. Natural substances, we claimed, could be a better therapeutic method.

The goal of the study was to see how effective the IMMUTONIC capsule was in treating flu symptoms in human volunteers.

The study included twenty-four male and female adult participants ranging in age from 21 to 60 years old.

Study Design: The study is a one-week randomised clinical trial. For one week, volunteers were given three IMMUTONIC capsules after each meal.

The improvement of flu symptoms was measured using a 0-to-5 improved health scale after 3 and 7 days.

Results: After 3 days of follow-up, flu symptoms and hunger improved significantly at p0.05, whereas health improved dramatically at p0.05 after 7 days.

Conclusion: Immutonic pill relieves Flu symptoms by improving the immune system and its antibacterial and viral actions, as well as increasing appetite, which leads to better feeding.

Author(S) Details

Hussien O. Alkadi
Sana’a University, Faculty of Medicine and Health Sciences, Sana’a, Yemen.

H. K. Mohamed
48 Model Hospital, Sana’a University, Yemen.

H. K. Taha
48 Model Hospital, Sana’a University, Yemen.

View Book:- https://stm.bookpi.org/RDMMR-V13/article/view/5032

Study on Fruit Based Dye Sensitized Solar Cell | Chapter 9 | Recent Trends in Chemical and Material Sciences Vol. 4

 In the field of solar energy conversion, finding a cost-effective and environmentally acceptable solar cell is always a scientific problem. As a result, Dye Sensitized Solar Cells (DSSCs), which offer low-cost production and attractive features, are gaining traction in the industry. Nanocrystalline mesoporous oxide film, dye sensitizer, electrolyte, redox couple, counter electrode, and conductive substrate make up dye sensitised solar cells. The dye sensitizer faces several key hurdles, including high production and material costs, a complicated and costly synthetic process, and an easy degradation problem for inorganic dye sensitizers. As a result, the alternative dye in DSSCs will be a dye with a large supply and low cost. Natural dyes appear to be a viable alternative dye since they are inexpensive, easy to obtain, have a large supply of raw materials, are non-toxic, and biodegrade completely. The performance of the fruit-based dye-sensitized solar cell over the years is reviewed in this article.

Author(S) Details

M. C. Ung
Energy and Materials Research Group, Faculty of Engineering, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.

C. S. Sipaut
Energy and Materials Research Group, Faculty of Engineering, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.

J. Dayou
Vibration and Sound Research Group, Faculty of Science and Natural Resources, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.

K. S. Liow
Energy and Materials Research Group, Faculty of Engineering, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.

J. Kulip
Biology Tropical and Conservation Institute, Universiti Malaysia UMS, 88400, Jalan Maktab Sabah, 88100 Kota Kinabalu, Sabah, Malaysia.

R. F. Mansa
Energy and Materials Research Group, Faculty of Engineering, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.

View Book:- https://stm.bookpi.org/RTCAMS-V4/article/view/4801