This chapter aimed to correlate serum magnesium levels with
renal parameters in patients with Acute kidney injury (AKI) patients.
AKI is a prevalent condition with a range of causes and
effects, including electrolyte imbalances that can manifest as hyperkalemia,
hypocalcemia, or hypocalcemia depending on the stage. One of the most frequent
electrolyte abnormalities seen in hospitalized patients, particularly in the
critically ill, is hypomagnesemia. As a result, we made the decision to
investigate the relationship between serum magnesium levels and AKI.
A total of 100 patients from those attending medicine OPD
and getting admitted in medicine ward, Victoria &Bowring hospital, attached
to Bangalore medical college and research institute, during the period of
November 1st 2016 to august 30th 2018 was taken for the study. The decrease in
magnesium <1.7 mg/L was defined as hypomagnesaemia. AKI was defined as per
AKIN criteria. Day 1, day 3 and day 6 magnesium levels were measured.
Prevalence of hypomagnesemia was 53%, 30% and 36% on day 1,
day 3 and day 6 respectively. Out of 120 cases, 20 cases were excluded out of
which 4 were due to obstructive uropathy, 6 were suffering from multi-organ
dysfunction syndrome and 10 were diabetic. 66patients recovered from AKI and 34
did not recover, all 34 patients were treated with haemodialysis. It was
observed that there was a positive correlation between serum magnesium, and
serum creatinine. Normomagnesemia and hypermagnesemia on day 1,3 and 6 were
significantly associated with recovery of AKI (p=<0.001).
In AKI patients, hypomagnesemia was far more common, and recovery was correlated with normal magnesium and hypermagnesium levels on days 1, 3, and 6. Hypomagnesemia was linked to non recovery rather than improvement.
Author(s) Details:
Raveendra K. R.,
Department
of Medicine, Bangalore Medical College and Research Institute, KR Road,
Bangalore, Karnataka, India.
Avinash
H. R.,
Department
of Medicine, Bangalore Medical College and Research Institute, KR Road,
Bangalore, Karnataka, India.
Nitish Ashok Gurav,
Department of Medicine, Bangalore Medical College and Research
Institute, KR Road, Bangalore, Karnataka, India.
Please see the link here: https://stm.bookpi.org/ANUMS-V2/article/view/13087
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