This study investigated the possibility of using Moringa
oleifera seed extract to prevent poisoning caused by commercial lead
nanoparticles (CLNP) and induced by pulsed laser ablation (LLNP) in white
Wistar rats. The widespread use of lead increases environmental and health
challenge. A major exposure to lead affects the central and peripheral nervous
systems, leading to neuronal degeneration. The experimental animals were
divided into six groups, with seven rats in each group. Moringa and commercial
lead were given to the rats in accordance with standard methods. The experimental
period was 45 days. At the end of the exposure period, the rats were dissected.
Their liver and kidneys were removed and preserved in 10% formalin solution as
a fixative solution to prepare them for histological sections. Histological
imaging results showed that the CLNP group had prevascular cuffing of
inflammatory cells with binucleate hepatocyte and hydronic degeneration. In the
LLNP group, blood vessels were dilated, and the central vein and hepatocytes
had vascular degeneration. The changes in CLNP. M. and LLNP. M. groups were
less severe. In the kidneys, the changes in the LLNP group were indicated by
congestion in the blood vessels and inflammatory cell infiltration. Moringa
provides protection for liver cells because of its chemical components that
have protective properties against lead-induced hepatotoxicity. In the CLNP
group, kidney tissue imaging revealed congested blood vessels with the massive
dissolution of red blood cells and the proliferation of inflammatory cells.
Author(s) Details:
Abid A. Thaker,
Department of Medical Laboratories Techniques, Maarif University
College, Al-Anbar Governorate, Iraq.
Fiham
Jassim Al-Obaidi,
Department
of Biology, College of Science, University of Anbar, Iraq.
Asmiet Ramziy,
Department of Physics, College of Science, University of Anbar,
Iraq.
Please see the link here: https://stm.bookpi.org/ARBS-V8/article/view/13285
No comments:
Post a Comment