Efficacy of Combination of PRP and Stem Cell Application on Ultrasound and MRI Findings in Patients with Knee Osteoarthritis | Chapter 8 | Novel Research Aspects in Medicine and Medical Science Vol. 6

 This phase's objective is to assess the belongings of platelet-rich plasma analysis combined with mesenchymal stem containers derived from autologous fatty tissue on ultrasonography and magnetic reverberation imaging for the situation of knee osteoarthritis. Knee osteoarthritis is the second leading cause of disadvantage in the elderly after heart failure. Osteoarthritis of the knee most influences mobility. Severe knee osteoarthritis is the cause of restriction for many patients, increasing the healing costs of the family and people. 30 patients, 26 females, 4 men, mean age 58.63 ± 11.11, mean disease duration 5.3 ± 4.6 age, respectively 60 knee intersections were diagnosed accompanying osteoarthritis at stage II - III according to the Kellgren and Lawrence classifications. After ultrasound and magnetic reverberation imaging in the first time, all cases were injected accompanying platelet-rich plasma combined accompanying mesenchymal stem cells from autologous fatty tissue into two together knee joints. After situation 12 months by platelet-rich plasma injection linked with mesenchymal stem cells from similar adipose fabric: The thickness of articular cartilage on ultrasound raised significantly from 2.08±0.36mm to 2 ,48±0.36 mm with p<0.05. There were 52 intersections with raised cartilage thickness, equivalent to 86.67%. The surface of articular piece of animate skeleton on magnetic resonance comprehensively positions of the knee joint has upgraded, the difference was statistically significant. Particularly, the patellar joint upgraded from 1.56 ± 0.25 mm to 1.64 ± 0.21 mm with p < 0.05. Mesenchymal stem cells from similar adipose tissue were favorably used in the situation of knee osteoarthritis to increase cartilage girth on ultrasound and magnetic resonance, as a consequence enhancing the patella joint's motor function.

Author(s) Details:

Truong Sinh Cao,
Vinh Medical University Hospital, Vinh City, Vietnam.

Tuan Nguyen Viet,
Vinh Medical University Hospital, Vinh City, Vietnam.

Please see the link here: https://stm.bookpi.org/NRAMMS-V6/article/view/12145