With the proclamation the Department of Health and Human Services (HHS) of the United States, pandemic of SARS-CoV-2 (COVID-19) has properly ended on May 11, 2023. What we gain the deadly pandemic and are we ready for the next impasse are important questions that need expected answered. To this exertion, this review provides an modernize and summarizes the recent advances in the situation of the COVID-19 and in particular stressed the strategies in directing cytokine release syndrome (CRS) prompted by SARS-CoV-2. These strategies may determine examples when we face the warning of the next pandemic.The approaches for developing novel situations against COVID-19 include antiviral small fragment drugs, cell & deoxyribonucleic acid therapies, immunomodulators, neutralizing antibodies, and blend therapies. Among bureaucracy, immunomodulators are the most studied situations. The small particle antiviral drugs and immunoregulators are expected expected effective against aggressive variants of SARS-CoV-2 as these drugs target either conservative parts of the bacterium or common pathways of redness. Although the immunoregulators have shown benefits in lowering mortality of CRS caused by SARS-CoV-2 infections, extensive analyses on this class of treatment to begin novel therapies that extensively improve productiveness and reduce aftereffects are still warranted. Moreover, great challenges have arose as the SARS-CoV-2 virus fast, frequently, and steadily evolved.
Author(s) Details:
Long G. Wang,
Department
of Research and Development, Natrogen Therapeutics International, Inc.,
Valhalla, New York, USA.
Luxi Wang,
Department of Clinical
Research, Clinipace Clinical Research, Morrisville, North Carolina, USA.
Please see the link here: https://stm.bookpi.org/CPMMR-V4/article/view/11319
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