Aim: The purpose of this research was to compare normal
people to those undergoing chemotherapy for periodontal disease and to
determine the effect of the oral bacteria Entamoeba gingivalis and Trichomonas
tenax. Then determine the parasites' pathogenicity by studying them in live
organisms.
Materials and Methods: The research included 80
participants: 30 patients with periodontitis who visited the AL-Karama dental
clinic, and 20 patients undergoing chemotherapy who were sent to the national
center of hematology at Mustanasiriyah University in Iraq. In addition, the
remaining 30 people were seen as a control group with healthy teeth and gums.
Gum scrapings were promptly microscopically inspected using two methods: a
wet-mount smear and a Giemsa-Romanovesky stain. As part of the experiment, the
positive samples were cultivated on specific cultures and then applied to the
gingival margins of three groups of rats, one of which was given an
immunosuppressive medicine and the other two did not. This process was repeated
for each parasite.
Results: Entamoeba gingivalis is more common in
periodontitis patients (36.7% greater frequency), according to the data.
Chemotherapy patients had a 30% greater frequency of E. gingivalis and a 10%
higher frequency of Trichomonas tenax compared to the control group, whereas
the percentages for the other two bacteria were 15% and 3.333%, respectively.
There was no death, inflammation, or ulceration in the control group, but all
rats in the first group that dealt with E. gingivalis developed periodontal
ulcers; two rats in the second group died after 10 days; one rat in the third
group had mild gingival inflammation but was otherwise healthy; and all rats in
the fourth group dealt with T. tenax were still alive and had healthy gingiva.
Conclusion: Periodontal individuals had elevated E.
gingivalis frequencies, according to these results. Frequencies were greater in
the treatment group compared to the control group. People undergoing
chemotherapy may develop a harmful infection caused by In Vivo Entamoeba
gingivalis.
Author(s) Details:
Hayat Ghaith Sachit,
Basic Science Department of Microbiology, College of Dentistry, Mustanasiriyah University, Baghdad, Iraq.
Dhilal Mahdi Al-Muathen,
Basic Science Department of Biology, College of Dentistry, Mustanasiriyah University, Baghdad, Iraq.
Please see the link here: https://stm.bookpi.org/ANUMS-V3/article/view/13159
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