Thursday, 12 October 2023

Frozen Section Diagnosis: An Emphasis on Reasons, Accuracy and Errors for Discordance | Chapter 6 | Novel Research Aspects in Medicine and Medical Science Vol. 5

The purpose of the hearing was comparing rates of intra-functioning frozen section disease with last diagnosis on paraffin section in consideration of assess concordant, conflicting, and postponed diagnosis rates and to label the causes of discordance. The links of intra-operative stopped section diagnosis accompanying permanent section definitive diagnosis is a important aspect of surgical pathology control of product quality. A retrospective analysis of 117 cases of stopped section biopsy was completed activity which were stated in the Histopathology department between July 2007 to June 2012.  The equivalence between the frozen division diagnosis with ending histological diagnosis was acted in order to check the accuracy of the method.  The number and type of discrepancies were compared, causes for the conflicts were analysed in order to decrease the avoidable mistakes and improve on the stopped section diagnoses. The overall accuracy of stopped section diagnoses over 5years was 90.60% with fake positive rate of 0.85%, false negative rate of 6.84% and 1.71% of delayed diagnosis. Sensitivity was 87.69% and Specificity was 98%. The conflicts were mainly due to the understanding error, sampling wrong and technical artefacts. Gross inspection, pathologist sample, stopped sections linked with cytological and histological analysis, and cooperation among consultants can help to escape few restrictions and give intensely, trustworthy, and inexpensive information needed favorable possible patient treatment.

 Author(s) Details:


Roopam Kishore Gidwani,
Pathology Department, Medical College Vadodara, India.

Falguni Jay Goswami,
Pathology Department, Medical College Vadodara, India.

Arpan Mehta,
Neuberg Supratech Reference Laboratory, Ahmedabad, India.

Nirali V. Shah,
Pathology Department, Medical College Vadodara, India.

Shobhana Prajapati,
Pathology Department, Medical College Vadodara, India.

Manisha M. Shah,
Pathology Department, Medical College Vadodara, India.

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