Evaluation and Correlation of Raised Serum Alanine Transaminase Values in Reference with Obesity | Chapter 2 | Current Innovations in Disease and Health Research Vol. 6

 This study was planned to access the level of alanine transaminase in corpulent subject in the population of Peshawar city, Khyber Pakhtunkhwa, Pakistan. Obesity is the end result of an inequality between strength expended and consumed, that causes abnormal fat development in the body's tissues. Epidemiological, dispassionate, and animal studies have reported the role of oxidative stress in the pathogenesis of corpulence and its mixed risk factor. Obesity further leads to the development of cardiovascular disease and heart failure mortality alone of other cardiovascular risk factors. The current research was administered in RMI Hospital, Peshawar KPK Pakistan during December 2018 to June 2019. A total of 300 population who appears to be obese (159 women and 141 males) was checked during the entire ending for obesity utilizing BMI. Out of 300 cases, 148 (49.3%) cases were separated in the types of obese individuals contingent upon body bulk index values in accordance with WHO criteria. Female with raised body bulk index were 71 (48.0%) and 77 (52.0 %) were males. About 35 (46%) male patients presented elevated Alanine Aminotransferase level and 24 (33.8%) women. In both male and female accompanying increase body mass index granted elevated antitoxin Alanine Aminotransferase. The prevalence of increased ALT principles in obese cases (BMI greater than or effective 31 kg/m2) was more than eight times that in those accompanying normal pressure (BMI less than or prepared 25 kg/m2), even after allowing for the confusing effect of alcohol devouring. From this study, it was concluded that there is comparably increase in serum Alanine Aminotransferase overflowing increase in body bulk index and this raised enzyme levels is more low in obese men than obese females.

Author(s) Details:

Usman Wajid,
Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.

Amina Arif,
Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.

Shafia Arshad,
Faculty of Medicine and Allied Health Sciences, The Islamia University of Bahawalpur, Pakistan.

 Please see the link here: https://stm.bookpi.org/CIDHR-V6/article/view/11836