Saturday 30 September 2023

Acridine and Acridinedione: Synthesis and Biological Applications | Chapter 11 | Novel Aspects on Chemistry and Biochemistry Vol. 7

 The devote effort to something acridinediones has increased over the past various decades, which has unlocked the door to new applications in the technical, medical, and artificial domains. This is because acridinediones are an main class of nitrogen heterocyclic compounds that include excellent,4-dihydropyridine parent nucleus. This book episode covers the application of miscellaneous catalysts and methodologies, in the way that nanocatalysts, ionic fluids, microwaves, and ultrasound, in the development of synthetic contracts. It also specifies an overview of the historical framework, chemical backlashes, and physical and chemical traits of acridine/acridinedione derivatives. In addition, we have argued the results of the monomethoxy polyethylene glycol (mPEG) attached acridinedione compounds that were synthesized by our group and their organic applications, to a degree anticancer, antioxidant, and anti-microbial activity. The purpose concerning this discussion search out provide motivation for further search on the synthetic principles and mechanistic riddles associated with the acridinedione moiety for the improvement of mankind.

Author(s) Details:

Tathagata Dey,
Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India and Department of Pharmaceutical Chemistry, East Point College of Pharmacy, Bangalore-560049, Karnataka, India.

Dhakshanamurthy Thirumalai,
Department of Chemistry, Thiruvalluvar University, Vellore-632 115, Tamil Nadu, India.

Srinivasan Parthiban Ragavi,
Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India.

Indira Viswambaran Asharani,
Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/NACB-V7/article/view/11969

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