Friday, 3 March 2023

Phytochemical Assessment of Bioactive Constituents Derived from Punica granatum, Eriobotrya japonica and Musa acuminata Extracts against Hyperglycemic-induced Oxidative Trauma in Rat Model: A Histopathological Exploration | Chapter 6 | Current Topics on Chemistry and Biochemistry Vol. 9

 The antidiabetic and antioxidant characteristics of the leaf extracts of Punica granatum, Eriobotrya japonica and Musa acuminata were investigated utilizing usual and streptozocin (STZ) induced diabetic rats. The diabetes in rats was inferred by injecting STZ (40 mg/kg) intraperitoneally. The crude methanolic leaf extracts of P. granatum, E. japonica, and M. acuminata were executed verbally to the diabetic rats at a dose of 50 mg/kg for 28 days, in addition to the standard drug glimepiride (2 mg/kg). The effect of the leaf extracts on glucose fortitude was also proven in non-diabetic rats. Blood glucose levels were calculated at 0, 30, 60, and 120 minutes subsequently administration. The results were resolved utilizing two-way Analysis of Variance and articulated as standard deviation. The results displayed that the leaf extracts have important antidiabetic and antioxidant properties. These curative plants have the prospective expected an economical beginning of inborn medicine for the situation of diabetes.

Author(s) Details:

Rahat Mustafa,
Department of Chemistry, The University of Lahore, Lahore, Pakistan.

Shahana Rahat,
Department of Anesthesia, Evercare Hospital Lahore, Lahore, Pakistan.

Mazhar Abbas,
Department of Basic Sciences (Section Biochemistry), University of Veterinary and Animal Sciences, Lahore (Jhang-Campus), Jhang, Pakistan.

Munawar Iqbal,
Department of Chemistry, Division of Science and Technology, University of Education, Lahore, Pakistan.

Arif Nazir,
Department of Chemistry, The University of Lahore, Lahore, Pakistan.

Please see the link here: https://stm.bookpi.org/CTCB-V9/article/view/9758

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