Hypothyroidism in Mother and Child during Pregnancy and Its Effect on Fetomaternal Outcome | Chapter 5 | Research Developments in Medicine and Medical Science Vol. 2

 This practical, cross-sectional study aimed to study predominance of hypothyroidism in pregnant mom and autoimmunity among them.  The fetomaternal consequence of the study population is also intentional. Study population contained 142 pregnant mothers in 3rd term of pregnancy. fT4, TSH concentration were calculated from maternal antitoxin and cord blood. TPO agent for negating the effect of an infection or poison was estimated in maternal antitoxin. Maternal pregnancy effects were measured in terms of antepartum and postpartum bleed, as well as anaemia. The APGAR score and the baby's birth burden were used to assess before birth outcome. Prevalence of hypothyroidism was 28.87%, but Prevalence of thyroid autoimmunity was 18%. The incidence of unfavorable maternal outcome was establish to be statistically meaningful in hypothyroid state for maternal anaemia (Hb% <10mg/dl) [odds percentage 2.32, p value = 0.0096].  Adverse foetal outcome was raise to be statistically meaningful in hypothyroid state for the following parameters: Low birth burden (<2.5 kg) [odd ratio 2.37, p profit= 0.026], Low APGAR score [odd percentage 14.25, p value < 0.0001].

Author(s) Details:

Soma Gupta,
Department of Biochemistry, NRS Medical College, Kolkata, India.

Sanchayan Sinha,
Department of Biochemistry, College of Medicine and Sagore Dutta Medical College, Kolkata (Previously Attached as Junior Resident, Department of Biochemistry, NRS Medical College, Kolkata), India.

Please see the link here: https://stm.bookpi.org/RDMMS-V2/article/view/9956