The Role of Vitamin D in the Occurrence and Severity of Coronary Artery Disease: Experience from Western India Study | Chapter 1 | Research Developments in Medicine and Medical Science Vol. 5

 Background: The aim concerning this study was to interrogate the potential correlation between Vitamin D imperfection (VDD) and the severity of heart failure artery affliction (CAD) in patients who were experiencing coronary angiography, likely that VDD is a prevalent issue in evolving nations and has existed linked to atherosclerosis and CAD in recent research.Materials and Methods: In this explanatory cross-sectional study, successive patients accompanying acute coronary disease or effort disease of the heart who met with coronary angiography were enrolled. Vitamin D levels were calculated and CAD was defined as not completely one ship stenosis >50% on heart failure angiography. The study aimed to correlate Vitamin D confirm the severity and number of bowls involved in addition to traditional CAD risk factors.Results: In the study, it was noticed that 70.72% of the population endured from Vitamin D deficiency. Patients were classification based on their blood levels as bearing normal Vitamin D levels (> 30ng/ml), Vitamin D lack (20-30ng/ml), and Vitamin D deficiency (<20ng/ml). In the group of inmates with normal coronaries, only 2 in a group the total had Vitamin D Deficiency, which gives reason for 12.5%. Among those with Single Vessel Disease (SVD), 57 lacking the total had VDD, accounting for 70.37%. In the group of inmates with Double Vessel Disease (DVD), 91 out of the total had VDD, that accounts for 73.98%. For sufferers with Triple Vessel Disease (TVD), 36 exhausted the total had VDD, which accounts for 83.72%. The results determined that Vitamin D levels were inversely compared with important coronary artery ailment, both in conditions of the number of vessels complicated and their severity (p<0.001), as well as dyslipidemia (p=0.009). However, skilled was no significant equating found 'tween Vitamin D deficiency (VDD) and different conventional risk factors, containing age, diabetes mellitus, gender, hypertension and hot.Conclusion: The study found a extreme prevalence of Vitamin D deficiency with patients the one underwent heart failure angiography, and a significant correlation 'tween Vitamin D deficiency and the predominance and severity of CAD. However, further studies including larger societies are necessary to determine if Vitamin D supplementation can forestall the progression of atherosclerosis and the growth of CAD.

Author(s) Details:

Cinosh Mathew,
Department of Cardiology, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, 391760, Vadodara, Gujarat., India.

Sara Mary Thomas,
Department of Anaesthesia, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, 391760, Vadodara, Gujarat., India.

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