Anti-proliferative Effect on Breast Cancer Cell Line via Novel Biogenic Peptide Functionalized Silver Nanoparticles Synthesized from Aloin | Chapter 3 | Challenges and Advances in Pharmaceutical Research Vol. 8

 The current study aims to synthesise tableware( Ag) nanoparticles using Aloin with a focus on antibacterial, antioxidant, and anticancer exertion. The biosynthesis of nanoparticles has been designed as a profitable and environmentally friendly volition to chemical and physical styles.

The UV-Visible diapason was used to determine the tableware nanoparticles, which were synthesised using Aloin. Scanning electron microscopy( SEM), zeta eventuality, and dynamic light scattering( DLS) were used to further characterise it. The Aloin was also subordinated to a Fourier transfigure infraredanalysis.The immersion peak at 439nm in the UV-Visible immersion diapason of the synthesised tableware nanoparticles demonstrates the conformation of tableware nanoparticles in result. The shape of the Ag nanoparticles was revealed by SEM analysis. The IR gamuts revealed that Aloin excerpt contains six functional groups. The nanoparticles synthesised are largely stable, with an average flyspeck size of130.7 nm, as verified by zeta eventuality and DLS analysis. The nanoparticles produced were antibacterial and antioxidant in nature. It has a strong cytotoxic effect on bone cancer cell lines. According to the current study, the conflation route can be used on a large scale in the food assiduity for food preservation and these Ag nanoparticles can be used for its remedial purposes to develop a new medicine to treat cancer because it isn't dependent on factors like high energy, dragged medication times, and specialised outfit.

Author(s) Details:

F. Janeeta Priya,
PG & Research Department of Chemistry, Holy Cross College, (Affiliated to Bharathidasan University), Tiruchirappalli, Tamil Nadu, India.

A. Leema Rose,
PG & Research Department of Chemistry, Holy Cross College, (Affiliated to Bharathidasan University), Tiruchirappalli, Tamil Nadu, India.

S. Vidhya,
PG & Research Department of Chemistry, Holy Cross College, (Affiliated to Bharathidasan University), Tiruchirappalli, Tamil Nadu, India.

A. Arputharaj,
Department of Electronics, St. Joseph’s College, (Affiliated to Bharathidasan University), Tiruchirappalli, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/CAPR-V8/article/view/8491