Diabetes mellitus is a metabolic complaint with multiple etiologies characterised by habitual hyperglycemia and disturbances in carbohydrate, fat, and protein metabolism caused by blights in insulin stashing, insulin action, or both. There was a significant increase in blood glucose, glycosylated hemoglobin and attendant drop in tube insulin in STZ convinced rats were regressed back to near normal in diabetic rats treated with cassia fistula and glibenclamide treated rats. The current study demonstrates that STZ- convinced diabetic creatures have increased oxidative stress. In experimental rats, the ethanolic excerpt of cassia fistula flowers exhibits significant antihyperglycemic as well as antioxidant exertion. Our result is harmonious with the results of who reported a drop in antioxidant enzymes similar as SOD, CAT and glutathione peroxidase in diabetes mellitus. The presence of phytochemicals enhances cassia fistula flowers' capability to cover the towel defence system against oxidative damage in STZ- convinced diabetes. Our results indicate that the preventative goods of cassia fistula flowers may be due to inhibition of lipid peroxidation and scavenging of free revolutionaries by its antioxidant nature.
Author(s) Details:
K. A. Jeyanthi,
Department of Microbiology, Thanthai Hans Roever College (Autonomous), Perambalur–621220, Tamilnadu, India.
Please see the link here: https://stm.bookpi.org/CAPR-V8/article/view/8495
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