Neurological Complications in Tsutsugamushi Disease (Scrub Typhus) from Northeastern Region of India | Chapter 7 | Current Overview on Disease and Health Research Vol. 5

 The thing of this study was to characterize neurological complications in mite typhus from northeastern region of India.

We conducted a prospective study of mite meningoencephalitis at North Eastern Indira Gandhi Regional Institute of Medical lores among cases admitted to sanitarium between October 2009 and November 2011. The clinical filmland of mite typhus are generally associated with fever, rash, myalgia, and verbose lymphadenopathy. The opinion was made grounded on the clinical filmland, presence of an eschar, and a positive Weil – Felix test( WFT) with a titer of> 1160 and if needed a positive mite IgM enzyme linked immunosorbent assay. Lumbar perforation was carried out on cases with headache, nuchal severity, altered sensorium, or cranial whim-whams poverties, and glamorous resonance imaging( MRI) brain was performed if necessary.

The study included 23 cases with mite typhus meningitis who were serologically verified. There were 13 men and 10 women. Fever ≥ 1 week was the most common incarnation(39.1). Unexpectedly, none of them had an eschar. Median cerebrospinal fluid( CSF) cell count, lymphocyte chance, CSF protein, CSF glucose/ blood glucose, CSF ADA were 17 cells/ μL, 90, 86 mg/ dL,0.6605 and3.6 U/ mL, independently. Doxycycline was administered to all cases. In our study, there was no death.

mite typhus can not be ruled out in the absence of Eschar. Because clinical features and CSF findings can be incorrect for tuberculous meningitis, misdiagnosis may affect in gratuitous long- term empirical antituberculous remedy in cases of lymphocytic meningoencephalitis. Detainments in treatment have the eventuality to be fatal. In resource-poor countries, WFT remains a useful and affordable individual tool for this complaint.

Author(s) Details:

S. R. Sharma,
Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

H. Masaraf,
Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

K. G. Lynrah,
Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

M. Lyngdoh,
Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

Please see the link here: https://stm.bookpi.org/CODHR-V5/article/view/8444