This chapter is aimed to review the mechanisms and biomarkers for oxidative stress development in preeclampsia. Hypertensive diseases of gestation and their complications are one of the leading causes of motherly and fetal morbidity and mortality. In normal gestation, optimum irruption of trophoblast in uterine helical arterioles is achieved leading to vasodilation of these arterioles. This process is necessary for placental and fetal growth and well- being. bloodied trophoblastic irruption is noted in maters with preeclampsia( PE) which causes placental hypoxia and hypoperfusion. Placental hypoperfusion and hypoxia lead to the development of inflammation, endothelial dysfunction, and oxidate stress in maters with PE. Experimenters have linked colorful labels to estimate the position of oxidative stress and antioxidant capacity. farther studies are demanded to establish the mileage of these labels in the opinion, prognostic, and monitoring of PE.
Author(s) Details:
Amit D. Sonagra,
Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Ragini Singh,
Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Sagar Dholariya,
Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Anita Motiani,
Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Deepak Parchwani,
Department of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Please see the link here: https://stm.bookpi.org/CIMMS-V5/article/view/8468
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