As a result of industrialisation and the rapid development of new
components for cosmetics, a number of rules and guidelines have been developed
to regulate their usage, protect consumers, assign duties, and allow for claims
of adverse effects. Cosmetic products may be exposed to microbial contamination
during storage or transport. Cosmetics should be protected from microbial
contamination, just like any other product that contains water and organic or
inorganic substances, to ensure customer safety and extend their shelf life.
The aim of the study is to develop antimicrobial strategies in cosmetic
formulation to ensure product safety and stability. The most popular technique
involves applying antimicrobial agents, which can be natural or manufactured
substances or even multipurpose components. The use of good manufacturing
practices (GMPs), raw material management, and appropriate procedures, such as
the challenge test, to verify the preservative effect, are the current steps in
the validation of a preservation system. Microbiological testing should be
performed on each component before use, and any contamination should be removed
before mixing. It is recommended that the process water be cooled after boiling
for 30 minutes and that sterile water be added to make up for any evaporation
loss. Cosmetic products used for the eye area are very sensitive and should be
completely free from Staphylococcus
aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa strains. Some
microbes considered nonpathogenic may become opportunistic pathogenic. In a
stability study, it is indicated that products remained stable up to twelve
weeks of study with good antimicrobial activity, so it indicates that long-term
use of creams and ointments could bring about the desired purpose of
antimicrobial property for daily users.
Author(s)
Details
Dipak Kumar Singha
Calcutta Instt of Pharm Tech & AHS, Uluberia, Howrah, India.
M.
Chakraborty
Flemming College of Pharmacy, Baruipur, India.
R. N.
Pal
Calcutta Instt of Pharm Tech & AHS, Uluberia, Howrah, India.
Please see the book here:- https://doi.org/10.9734/bpi/mbrao/v4/5775
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