Unnatural Amino Acids (UAA) are key structural units of various
natural products, bioactive molecules, and drugs. Chiral pool, asymmetric
synthesis, and racemic synthesis were explored in the synthesis of UAA. UAA
plays a very important role in bioconjugation, organocatalysis, labelling of
bacterial cells, etc. UAA is used in bioconjugation for attaching fluorophore
and small molecules for labelling and drug delivery. Here in this chapter, we
discuss the recent synthesis of unnatural amino acids and their applications in
total synthesis and biological studies.
Author(s) Details
Anija
Mol T Philip
Department of Chemistry, Hislop College, Nagpur 440001,
Maharashtra, India.
Shoeb R
Khan
Department of Chemistry, Hislop College, Nagpur 440001,
Maharashtra, India.
Mayur
V. Khedkar
Department of Chemistry, Hislop College, Nagpur 440001,
Maharashtra, India.
Shibin
Chacko
Department of Chemistry, Hislop College, Nagpur 440001,
Maharashtra, India.
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