Background: Ovine pulmonary adenocarcinoma (OPA) is a contagious,
neoplastic lung disease of sheep that causes significant animal welfare and
economic issues throughout the world.
Aims: The study aims to provide a preliminary estimate of the
prevalence of OPA among slaughtered
sheep in eastern Libya and to delineate the morphopathological characteristics
of OPA in native Libyan sheep.
Methods: This study was carried out in the El-Beida
slaughterhouses located in Eastern Libya during October 2020- March 2023. The
lungs of 641 sheep carcasses were examined. The gross examination of these
lungs was carried out with respect to size, colour and consistency. The lungs
with gross lesions (n = 322) were collected and subjected to histopathological
examination.
Results: In 1.56% of total carcasses examined and in 3% of
abnormally appearing lungs, OPA lesions were discovered. The classical form was
present in 8 of 10 confirmed cases of OPA, and two presented with atypical
lesions. The disease manifests through progressive transformation of the
pulmonary epithelium, and the histopathological lesions in both forms were
generally comparable and comprised typical neoplastic proliferations of
alveolar and bronchiolar epithelium with inflammatory infiltration of variable
degrees.
Conclusion: This report confirms the existence of OPA in the
native sheep of the El-Beida area, with the occurrence of both the classical
and the atypical types. The morphopathological findings form useful diagnostic
references for standard pathological examination and emphasise the imperative
for further investigations on the epidemiology, etiologic factors, and
pathogenesis of OPA in Libyan sheep populations.
Author(s) Details
Zahra
M. A. Mohammed
Department of Pathology and Clinical Pathology, Faculty of
Veterinary Medicine, Omar Al-Mukhtar niversity, El-Beida, Libya.
Please
see the book here:- https://doi.org/10.9734/bpi/mbrao/v4/5558
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