Background: The
longevity of cell membranes is essential to avoid changes related to aging.
Photoaging damages collagen, elastin, and the skin’s moisture barrier, leading
to wrinkles, sagging, toughening, and dry skin texture. Rose hips, the red
fleshy berries of the dog rose (Rosa canina), have been known to have
medicinal properties since the time of Pliny the Elder (23–79 BC).
Objective: The
primary objective of this study is to evaluate the effects of a rose hip powder
(Hyben Vital®) made from seeds and shells of subspecies Lito, on
cell senescence, skin wrinkling, and aging.
Methods: A
total of 34 healthy subjects, aged 35–65 years, with wrinkles on the face
(crow’s- feet) were subjected to a randomized and double-blinded clinical study
of the effects of the rose hip powder, as compared to astaxanthin, a well-known
remedy against wrinkles. During the 8-week study, half of the participants
ingested the standardized rose hip product, while the other half ingested
astaxanthin. Objective measurements of facial wrinkles, skin moisture, and
elasticity were made by using Visioscan, Corneometer, and Cutometer at the
beginning of the study, after 4 weeks, and after 8 weeks. Evaluation of
participant satisfaction with both supplements was assessed using
questionnaires. In addition, the effect of the rose hip preparation on cell
longevity was measured in terms of leakage of hemoglobin through red cell
membranes (hemolytic index) in blood samples kept in a blood bank for 5 weeks.
In the comparative study of the effects of rose hip vs astaxanthin on the facial
skin, the magnitude of changes over time (i.e., baseline to 4–8 weeks) for the
same patient were analyzed by one-way analysis of variance (ANOVA). The
significance of all values was attained with P#0.05.
Results: In
the double-blinded study, the rose hip group showed statistically significant
improvements in crow’s-feet wrinkles (P,0.05), skin moisture (P,0.05),
and elasticity (P,0.05) after 8 weeks of treatment. A similar
improvement was observed for astaxanthin, with P-values 0.05,
0.001, and 0.05. Likewise, both groups expressed equal satisfaction with the
results obtained in their self-assessments. The rose hip powder further
resulted in increased cell longevity of erythrocyte cells during storage for 5
weeks in a blood bank. Comparing the effectiveness between the two treatments,
there was no significant difference in the skin improvement effect between rose
hip powder and the well-known antiwrinkle and antiphotoaging remedy
astaxanthin.
Conclusion: Results
suggest that intake of the standardized rose hip powder (Hyben Vital®)
improves aging-induced skin conditions. The apparent stabilizing effects of the
rose hip product on cell membranes of stored erythrocyte cells observed in this
study may contribute to improving cell longevity and obstructing skin aging.
Author(s) Details
L. Phetcharat
School of Antiaging and Regenerative Medicine, Mae Fah University, Bangkok,
Thailand and Department of Anti-Aging and Regenerative Medicine, Mae Fah
University, Bangkok, Thailand.
K. Wongsuphasawat
School of Antiaging and Regenerative Medicine, Mae Fah University, Bangkok,
Thailand and Department of Anti-Aging and Regenerative Medicine, Mae Fah
University, Bangkok, Thailand.
K. Winther
Institute for Nutrition, Exercise and Sports, University of Copenhagen,
Frederiksberg C, Denmark.
Please
see the book here:- https://doi.org/10.9734/bpi/dhrni/v2/1445
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