For the stability of dental implants and artificial joints, excellent solid bonding between biomaterials and bone tissue (osseointegration and osteo-conductivity) is critical. Much has been learnt about this notion, leading to substantial advances in implant design and surface modification in the fields of implant dentistry and orthopaedic surgery.
We studied whether low-intensity pulsed ultrasound (LIPUS) could accelerate the osseointegration ability of bioactive materials such as bioactive titanium and hydroxyapatite for this issue.
Bio-active pure titanium and hydroxyapatite (HA) were used as materials, and an in vitro simulation test and an animal experiment were conducted.
The production of bone-like hydroxyapatite on the material surface in simulated body fluid (SBF) under LIPUS was evaluated in a simulation test. The bio-active samples implanted to the rabbits' femurs, which underwent LIPUS irradiation, were studied using Scanning Electron Microscope (SEM), X-ray diffraction (XRD), and histological observation in an animal test.
As a result of the crystal growth of bone-like apatite on the surface of the sample materials, LIPUS irradiation showed excellent enhancement of bone-material attachment, implying that LIPUS application has clinical potential to improve osseointegration (osteointegration), bone-bonding ability of bio-active materials.Author(S) Details
Masanori Kobayashi
Department of Physical Therapy, College of Life and Health Sciences, Chubu University, 1200 Matsumoto-cho, Kasugai-City, Aichi, 487-8501, Japan.
View Book:- https://stm.bookpi.org/RDMMR-V9/article/view/4594
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