In aerobic species, free radicals are produced naturally as a result of mitochondrial action. Normally, cells have numerous mechanisms for scavenging free radicals; however, in certain pathologic processes, such as cancer, the number of free radicals increases, making it impossible to maintain the system's integrity, resulting in oxidative stress. Ruta graveolens L. (Rue) is a plant that grows in the Ruta family. attach to simple carbohydrates, allowing them to target cancerous cells and kill them through apoptosis while lowering free radical levels. Because rue stem lectins had never been researched before, we set out to characterise them. These lectins' anticancer and antioxidant properties were also studied. Rue stem lectins were isolated with a saline solution and semipurified before being given to nickel oxide-treated mice. The tiobarbituric acid (TBARS) method was used to measure Malondialdehyde (MDA), the Griess method to measure Nitrites, and the enzymatic activity of catalase to measure oxidative stress in the liver. In this research, Despite the fact that their antioxidant activity ratio is limited, making them a prooxidant agent at high concentrations, rue stem lectins have been proven to be useful as a medicinal auxiliar.
Author (s) Details
Amairany Torres-Alvarez
Unidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Mexico City 09230, México.
Ernesto Mendoza-Vallejo
Unidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Mexico City 09230, México.
Catalina Machuca-Rodríguez
Unidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Mexico City 09230, México.
View Book :- https://stm.bookpi.org/RRAB-V9/article/view/2003
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