Monday 26 July 2021

Magnetic Resonance Imaging (MRI) of the Brain in Cerebral Palsy Children | Chapter 3 | Highlights on Medicine and Medical Science Vol. 6

 Introduction: Cerebral palsy is one of the most common forms of severe juvenile disability, and it is linked to preterm birth in a unique way. Cerebral palsy is a general term for a variety of non-progressive movement impairments caused by brain injury before or shortly after birth. Symptoms such as muscle stiffness, involuntary movements, limited mobility, seizures, and others are prevalent. Cerebral palsy currently has no treatment and is treated symptomatically.

The goal of this study was to look into the many types of brain lesions that children with clinically diagnosed cerebral palsy have, as well as the relationship between MRI brain results and the type of cerebral palsy they have.

A total of 60 instances of cerebral palsy were evaluated utilising a history and clinical examination. Children with cerebral palsy were evaluated using neuroimaging (MRI). The MRI scans were performed on a GE Sigma 1.5 Scanner. T1 Weighted, T2 Weighted, and FLAIR (axial, coronal, and sagittal) sequences were routinely obtained. The scans of each patient were examined for any aberrant signals in the brain parenchyma, as well as myelination of the brain based on the baby's age and ventricle size.

The age group 1-2 years had the highest percentage of children (36%) followed by 30 percent in the age group 1 year and 18 percent in the age group 3-4 years. Males made up 61.66 percent of the 60 cases, while females made up 38.33 percent. Preterm delivery was the most common (60 percent), followed by term delivery (40 percent ). The majority of the individuals had spastic quadriplegia cerebral palsy. Periventricular leukomalacia was the most common abnormality found on imaging. A corpus callosum agenesis was found in one ( percent) of the patients.

Conclusion: MRI scans contribute in the uncovering of the disease's pathologic underpinnings, with MRI brain findings revealing a strong link to clinical outcomes.

More research is needed to understand the relationship between the location of brain lesions, their structure, and clinical functions in children with CP, as these are key criteria for studying reorganisation and plasticity.

Author (s) Details

Niyati Sharma
Department of Radiodiagnosis, Jawaharlal Nehru Medical College, AVBRH, Sawangi, Wardha, Maharashtra, India.

Rajasbala Dhande
Department of Radiodiagnosis, Jawaharlal Nehru Medical College, AVBRH, Sawangi, Wardha, Maharashtra, India.

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