Cancer stands as one of the most common causes for death of the individual worldwide. Radiotherapy is one of the treatment modalities in cancer where, exposure of the normal tissue to these ionising radiations, results in mutagenesis and cell death. Several modalities and clinical methods have been made to lessen these early and late problems of the radiotherapies and one of them is, by the means of pharmacological drugs. New notions of chemical and molecular pharmacological agents as radioprotective agents have emerged as a result of several experimental and clinical research. These have been utilised to avoid tissue damage from the radiations produced during the diagnostic and therapy phases of carcinomas. The clinical implications of these radioprotective compounds have emerged as promising drugs and with anti-tumour effect in the radiotherapy of various cancers, including oral carcinomas, to prevent the severe problems in irradiated patients.
Author (s) Details
Ugrappa Sridevi
AIMST Dental Institute, AIMST University, Semeling-Bedong, Kedah, Malaysia.
Ajay Jain
AIMST Dental Institute, AIMST University, Semeling-Bedong, Kedah, Malaysia.
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