Evaluation and Determination of the Antioxidant Capacity of the Crude Extracts of Some Medicinal Plants | Chapter 4 | Technological Innovation in Pharmaceutical Research Vol. 8

 DPPH, H2O2, and FRAP test methodologies were used to evaluate the antioxidant capabilities of ten (10) plant species from distinct Nigerian states. Piliostigma reticulatum had the best scavenging property at the lowest concentration (6.25 g/ml), while C. accuminata had the best scavenging property at the highest concentration (100 g/ml) in the DPPH assay. P. reticulatum> A. digitata> T. indica> C. accuminata> V. paradoxa> B. diezelli> S. longipediculata> A. squamosa> P. biglobosa> S. singueana is the trend at the lowest concentration. C. accuminata> B. diezelli> T. indica> P. biglobosa> A. digitata> V. paradoxa> A. squamosa> P. reticulatum> S. longipediculata> S. singueana is the trend at the maximum concentration. B diezelli showed the strongest scavenging performance at both the lowest (6.25) and maximum (6.25) concentrations in the H2O2 experiment (100). B. diezelli> A. squamosa> S. longipediculata> S. singueana> V. paradoxa> P. bigloosa> C. accuminata> A. digitata> T. indica> P. reticulatum at the lowest concentration At the top, the trend is B. diezelli>S. longipediculata> S. singueana> V. paradoxa> P. paradoxa. P. reticulatum> C. biglobosa> P. biglobosa> P. reticulatum> C. biglobosa> A. accuminata T. digitata> indica. The FRAP assay indicates that S. At the lowest concentration (6.25), longipediculata showed the highest scavenging action, while C. At the highest concentration, accuminata had the most action. At the lowest concentration, the pattern is as follows: S. C. longipediculata> T. accuminata> A. indica> A. digitata> V. paradoxa> digitata> V. paradoxa> digitata> V. paradoxa Squamosa> P. reticulatum> P. biglobosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamos B. singueana> diezelli. The tendency is C. at the highest concentration. S. accuminata> T. longipediculata> A. indica> A. digitata> Squamosa> V. paradoxa> P. reticulatum> P. biglobosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamosa> Squamos B. singueana> diezelli. Five (5) crude extracts (S. longepedicunlata, T. indica, A. digitata, A. squamosa, C. accuminata) were more active in the FRAP assay at higher doses than the reference drugs (ascorbic acid and butylated hydroxyl anisole). In the DPPH experiment, the methanol crude extract of Piliostigma reticulatum was more active than any other plant materials. The methanol crude extracts of Annona squamosa and Parkia biglobosa were more active in the hydrogen peroxide assay than the other extracts.

Author (s) Details

Hassan B. Yesufu
Department of Pharmaceutical Chemistry, University of Maiduguri, P.M.B 1069, Maiduguri, Nigeria.

Ibrahim Iliya
Department of Pharmaceutical Chemistry, University of Maiduguri, P.M.B 1069, Maiduguri, Nigeria.

Fanna I. Abdulrahman
Department of Chemistry, University of Maiduguri, P.M.B 1069, Maiduguri, Nigeria.

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