Antibiotic resistance is a serious problem in the management
of childhood infections. Bacteria have
developed various mechanisms of resistance.
Indiscriminate and irrational use of antibiotics have led
to the emergence of superbugs which have developed
resistance to multiple antibiotics. Nowadays
research are showing promising role of usage of older
antibiotics for treatment of resistant infections.
Multidrug resistant gram negative infections is a
challenging situation where combination therapy and
drugs with gram positive coverage like vancomycin are
showing positive results. Ampicillin is losing
sensitivity and protocols have been modified in using
cephalosporins as the first line in some units.
Carbapenam resistance and ESBL are emerging among
hospitalised patients. Similarly emergence of
community acquired MRSA possessing a new virulence
toxin (Panton-Valentine leukocidin) is a
serious threat among childhood infections.
Unfortunately of late only minimal resources are directed to the development of newer antibiotics. Its time to consider
the emerging antibiotic resistance
particularly among children as a serious issue and
start rational antibiotic practice and develop unit
specific antibiotic policy to fight against antibiotic
resistance.
Author
(s) Details
Dr. C. Rabindran
Department of Neonatology, Billroth Hospital, No.43, Lakshmi
Talkies Road, Shenoy Nagar, Chennai, India.
Dr. V. Devendran
Department of Neonatology, Billroth Hospital, No.43, Lakshmi
Talkies Road, Shenoy Nagar, Chennai, India.
Dr. D. Velmurugan
Department of Neonatology, Billroth Hospital, No.43, Lakshmi
Talkies Road, Shenoy Nagar, Chennai, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/260
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