Introduction: Dengue fever is an arboviral disease caused by the
dengue virus transmitted by the bite of female Aedes aegypti mosquitoes,
affecting people worldwide and often causing pandemics in Southeast Asian
countries. The global health disease burden of dengue has been found to be the
highest among all arboviral diseases. Dengue viral infection symptoms range
from flu-like illness to complications like pneumonia, hepatitis, neurologic
symptoms like encephalitis, myopathy, Guillain–Barre syndrome, phrenic
neuropathy, subdural hematoma, and cerebral vasculitis. The possibility of
skeletal muscle invasion causing myositis is another rare entity.
Case Description: A case of dengue, with myositis presenting as
muscle weakness, decreased power, and raised Creatinine Phosphokinase (CPK)
level in a 6-year-old boy has been reported.
The boy suffered from Dengue viral fever diagnosed by positive NS1
antigen. Initially, the symptoms were like uncomplicated dengue fever but later
he developed leg muscle pain and, a decreased range of movements. The Serum CPK
level was increased and then the baby was diagnosed with myositis. Later with
supportive treatment, he improved, the pain subsided, the power and tone of leg
muscles increased and the serum CPK level came to normal. The child’s condition
was self-limiting and hence he was treated as per standard dengue national
management guidelines with antipyretics and regular monitoring of blood
pressure, hematocrit, platelet count, and level of consciousness.
Conclusion: Myositis in the pediatric population is a rare entity
and hence often neglected and undertreated. It can turn into permanent damage
and deformity if not treated in time in long-term sequelae.
Author
(s) Details
Sanchayan
Sinha
Faculty of Biochemistry, College of Medicine and Sagore Dutta
Hospital, Kolkata, India.
Anannya
Ghosh
Department of Clinical Chemistry, Immunology & Biochemical
Genetics, Suraksha Diagnostics Pvt. Ltd. Kolkata, India.
Please see the book here:- https://doi.org/10.9734/bpi/mmrnp/v7/2205
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