Because of its simplicity of genetic manipulation, faster generation time, availability of integrative and episomal vectors, and promoters that can be simply turned on and off using simple chemical moieties, the yeast Saccharomyces cerevisiae has been widely employed for heterologous protein production. Furthermore, as the simplest eukaryote, it has various benefits in the expression of mammalian proteins, such as post-translational modifications and the expression of membrane-bound proteins. The development of a strain for the production of membrane bound human drug metabolism enzymes is described in this article.
Author (S) Details
Rajeev Soni
Technical Operations, Genei Laboratories (a Rivaara Company), Bangalore, India.
View Book :- https://stm.bookpi.org/IMB-V1/article/view/3763
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