Uterine epithelioid leiomyosarcoma is a form of uterine mesenchymal tumour that develops from the smooth muscle that lines the uterus's walls. The exact cause of leiomyosarcoma is unknown, however it is thought that uterine leiomyosarcoma accounts for 5 to 10% of occurrences. Leiomyosarcoma, the most common subtype of uterine sarcoma, accounts for 1-2 % of all uterine cancers. Molecular approaches have recently been used to identify a number of lesions with specific genetic abnormalities and clinicopathological characteristics. Malignancy should be suspected in menopausal women who are not taking hormonal replacement therapy and have developed a tumour. A 64-year-old woman has been experiencing postmenopausal haemorrhage for the last two months, with a palpable lump approximately 16 weeks in size. On ultrasonography, the whorled mass lesions, endometrium, and myometrium could not be distinguished. Both ovaries have been removed from the uterus. A 16-week-old uterine tumour with a dimension of 15x15 cm and a weight of 1kg, as well as an intramural fibroid, were discovered during the procedure. Necrotic and haemorrhagic areas with degenerative modifications on cut sections signify malignancy. Histopathology and immunohistochemistry were used to find epithelioid leiomyosarcoma.
Author (S) Details
Upadhya Rekha
Department of Obstetrics and Gynecology, Kasturba Medical College, MAHE, Karnataka, India.
Vidyashree G. Poojari
Department of Obstetrics and Gynecology, Kasturba Medical College, MAHE, Karnataka, India.
Muralidhar V. Pai
Department of Obstetrics and Gynecology, Kasturba Medical College, MAHE, Karnataka, India.
Jayaraman Nambiar
Department of Obstetrics and Gynecology, Kasturba Medical College, MAHE, Karnataka, India.
View Book :- https://stm.bookpi.org/NFMMR-V16/article/view/3792
No comments:
Post a Comment