The purpose of this study is to analyse the phytochemical profile and antibacterial activity of Tecoma stans (L.) ethanolic extract (TSEE) against Gram-positive and Gram-negative bacteria in vitro, because plants are utilised as medicinal agents. Tecoma stans is a perennial flowering shrub of the Bignoniaceae family. The entire plant has therapeutic potential and is used to cure a variety of diseases. Cold maceration with ethanol was used to extract the dried flowers. Alkaloids, glycosides, saponins, sugars, tannins, phenolic compounds, steroids, and flavonoids were discovered among the phytoconstituents. Antimicrobial activity was tested using the agar well diffusion method against microorganisms such as Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis, Bacillus megaterium, Streptococcus mutans, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Proteus vulgaris. The antibacterial activity of the TSEE extract against these pathogens ranged from moderate to strong. The zone of inhibition has a diameter ranging from 20.330.57 to 09.331.52 mm, and the activity was compared to normal tetracycline. The inhibition range was reported to be 31.2 mg/ml to 125 mg/ml using the two-fold broth dilution method. MBC values range from 62.5 to 150 mg/ml. The findings demonstrate that Tecoma stans flowers contain phytochemicals that have broad spectrum antibacterial activity against pathogenic microorganisms evaluated in this study.
Author(s) Details
Sowjanya Pulipati
Vignan Pharmacy College, Vadlamudi- 522 213, Guntur (Dt), Andhra Pradesh,
India.
P. Srinivasa Babu
Vignan Pharmacy College, Vadlamudi- 522 213, Guntur (Dt), Andhra Pradesh,
India.
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