Diabetes mellitus is a metabolic disease characterised by chronic hyperglycemia and is associated with an increased risk of microvascular consequences. Serum sialic acid has been identified as a putative Type 2 diabetes risk factor. In Type-2 diabetics, serum sialic acid levels are frequently greater than in non-diabetic people.
The study's goal was to estimate serum sialic acid in patients with Type 2 Diabetes Mellitus and non-diabetic individuals in NCR, Delhi, and to compare serum sialic acid levels to fasting blood glucose levels in patients with Type 2 Diabetes Mellitus and non-diabetic individuals.
Materials and Methods: A cross-sectional assessment of 70 adults aged 30 to 70 was conducted in Delhi's NCR. Thirty-five persons with type-2 diabetes mellitus (15 men and 20 women) and thirty-five people without diabetes acted as controls in this study (16 males and 19 females).
Fasting blood glucose and serum sialic acid were measured in both groups.
Results: Type 2 diabetes mellitus patients had higher serum sialic acid levels (76.607.89) than non-diabetics (39.669.55), with a statistically significant p-value of 0.001.
Conclusion: Serum sialic levels were found to be greater in Type 2 diabetes patients in Delhi-NCR, indicating that these patients were at risk of developing microvascular issues, according to the findings of this study. As a result, measuring sialic acid levels could help in the early detection and prevention of microvascular issues linked to type 2 diabetes.Author(S) Details
Yendrembam Pascal Singh
Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Manoj Kumar Nandkeoliar
Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Ved Pal Singh Punia
Department of Medicine, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Gladys Rai
Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
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