Background: Pancytopenia is a common haematological problem characterised by the presence of anaemia, leucopenia, and thrombocytopenia all at the same time. The disease pattern linked with pancytopenia varies depending on geographic area, age group, nutritional status, drug intake, and infective condition prevalence. The purpose of this prospective study was to investigate and discover possible causes of pancytopenia, as well as to determine the percentage of people who have pancytopenia, as well as to compare the findings with those of other similar studies. From June 2012 to June 2014, 80 patients with pancytopenia were clinically assessed at Justice K. S. Hegde Hospital, Nitte University, Deralakatte, Mangalore, with full blood counts, peripheral smears, and bone marrow aspiration-biopsy whenever possible. Results: The majority of the 80 cases studied were in the 41-50 year age range, with a male predominance. The three most common reasons in our hospital were hypersplenism (28.75 percent), malaria (16.25 percent), and megaloblastic anaemia (13.75 percent). Plasmodium vivax (8 instances) was the most prevalent parasite found in 13 cases of malaria. Conclusion: Different causes of pancytopenia can be related to geographic location, nutritional and pharmacological intakes, personal habits, infectious causes, diagnostic criteria stringency, and variances in methodology used, according to the current study. Thus, in the comprehensive workup of patients with pancytopenia, a detailed clinical history and meticulous examination, as well as haematological assays, give vital information for understanding disease processes, planning additional investigations and management, and determining the cause.
Author(s) Details
Deptartment of Pathology, Akash Institute of Medical Sciences and Research Centre, Devanahalli, Bengaluru, India.
Shetty K. Padma
Deptartment of Pathology, K.S Hegde Medical Academy, NITTE University, Deralakatte, Mangalore, India.
K. Sajitha
Deptartment of Pathology, K.S Hegde Medical Academy, NITTE University, Deralakatte, Mangalore, India.
Jayaprakash Shetty
Deptartment of Pathology, K.S Hegde Medical Academy, NITTE University, Deralakatte, Mangalore, India.
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