Brainstem Projections of the Dorsolateral Hypothalamic Area | Chapter 3 | New Advances in Medicine and Medical Science Vol. 9

 This unit highlights about Brainstem projections of the dorsolateral hypothalamic district. The dorsolateral hypothalamic area (DLH) covers a nearly large, but not rigidly outlined extent in the posterior part of the hypothalamus. This area longers rostrocaudally from the level of the caudal facet of the paraventricular nucleus (about 2.4 mm posterior to the bregma level, in adult rats) until the level of the posterior end of the third ventricle (3.4 mm posterior to the bregma). The dorsolateral hypothalamic area maybe divided into 3 fields (dorsomedial hypothalamus, perifornical area, sideways hypothalamic area), and further subdivided into 8 subdivisions. After unilateral stereotaxic injections of biotinylated dextran amine (BDA) into individual DLH subdivisions, the allocation patterns of BDA-positive fibers were plan on serial portions between the hypothalamus and sleep-inducer cord in 22 rats. BDA-described fibers were observable over 100 various brainstem areas, nuclei or subdivisions. Each DLH subdivisions settled distinct terrestrial patterns, however mainly the density of labeled fibers was reduced in the lower brainstem. The present findings reinforce a significant portion of the dossier reported about the especially of touch pattern of the dorsolateral hypothalamus (DLH) to the lower brainstem in general, the judgment of the projections of the 8 individual subgroups provides us new facts. No definitive downward BDA-positive road, but long-run solitaire BDA-branded fibers were seen. Some of the major tracts or fasciculi in the brainstem were related by these descending fibers. Only 4 of the 116 positions had high texture densities: the Barrington's and pedunculopontine tegmental nuclei, and the ventrolateral and lateral portions of the periaqueductal muted silver in color. Knowing the precise neighborhoods of their neuronal inputs is important for understanding in what way or manner the lower brainstem functions because it holds significant instinctive and autonomic supervisory areas and nuclei, the reticular establishment, central noradrenaline and epinephrine neurons (including premotor responsive ones), and serotonin-meaning raphe nuclei. Some of the tegmental nuclei and nuclei of the reticular composition were widely innervated, although the bulk of the BDA-labeled fibers was mainly low.

Author(s) Details:

Rege Sugárka Papp,
Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest H-1094, Hungary and Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest H-1094, Hungary.

Miklós Palkovits,
Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest H-1094, Hungary and Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest H-1094, Hungary.

Please see the link here: https://stm.bookpi.org/NAMMS-V9/article/view/11168