Wednesday 28 June 2023

A Recent Study on Anti-microbial Properties of Some Novel Substituted Indazoles | Chapter 1 | Novel Aspects on Chemistry and Biochemistry Vol. 3

 A number of indazole descendants were reported as effective anti-bacterial and antimicrobial agents.  This stage outlines our efforts to expand synthesized indazole derivatives accompanying powerful antimicrobial ventures. A variety of N-methyl-3-aryl indazoles (5a-5j) were checked for their in-vitro antimicrobial effects.  The synthesized compounds were proven for antibacterial action against four bacterial strains: Xanthomonas campestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and Candida albicans.  The biological judgment studies of these indazole derivatives revealed that few of these tested compounds 5a, 5b, 5i and 5j displayed excellent inhibitory activity against various tested microbial strains.

Author(s) Details:

Jaganmohana Rao Saketi,
Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India and Department of Chemistry, Government Degree College, Palakonda, Andhra Pradesh, India.

S. N. Murthy Boddapati,
Department of Chemistry, Sir C R Reddy College, Eluru, Andhra Pradesh-534007, India.

M. Raghuram,
Department of Botany and Microbiology, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India.

Geetha Bhavani Koduri,
Department of Chemistry, IIIT-RGUKT, Ongole Campus, Andhra Pradesh, India.

Haribabu Bollikolla,
Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India and Department of Chemistry, Andhra Kesari University, Ongole, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/NACB-V3/article/view/11020

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