The question of obesity shows a increasing pattern. 25% of the population of the planet is obese with a bulk mass index (BMI) of 25-30 and about 8% is obese accompanying BMI over 30. Despite the high rate of depression, the pathogenesis of obesity underlying unrestrained eating action still has many uncovered aspects. Genetic and tangible factors, various regions of the CNS, various neurotransmitters, and neuropeptides, are complicated in the central means that control eating management.Physiologically food is consumed for homeostatic and hedonistic purposes, regulated by two obvious but closely interconnected orders: the hypothalamic and brain reward methods.Hedonic eating usually surpasses the caloric threshold for the physiologic requirement of the organism for strength and structural material. In this circumstances, dopamine and serotonin are considered ultimate important neurotransmitters. Hence, the endocannabinoid and opiate wholes also have happened shown to have particular weight in the managing of food consumption and sense of pleasure.In this chapter, we climax the main neurochemical regulators complicated in the peripheral and central devices of hedonic consuming causing overweight and corpulence.
Author(s) Details:
Hasmik S. Harutyunyan,
Biochemistry Department, Yerevan State Medical
University named after Mkhitar Heratsi, Yerevan, Armenia.
Gayane
S. Vardanyan,
Biochemistry
Department, Yerevan State Medical University named after Mkhitar Heratsi,
Yerevan, Armenia.
Alla L. Shaljyan,
Biochemistry Department, Yerevan State Medical University named after
Mkhitar Heratsi, Yerevan, Armenia.
Anahit V. Saharyan,
Biochemistry Department, Yerevan State Medical University named after
Mkhitar Heratsi, Yerevan, Armenia.
Mikhail
I. Aghajanov,
Biochemistry Department, Yerevan State Medical
University named after Mkhitar Heratsi, Yerevan, Armenia.
Please see the link here: https://stm.bookpi.org/RHDHR-V9/article/view/10973
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