Friday 30 June 2023

Comparison of Two Knee Prolotherapy Injection Methods in Reducing Pain and Improving the Function of Patients with Knee Osteoarthritis | Chapter 5 | New Advances in Medicine and Medical Science Vol. 7

 The present phase sought to equate the effect of periarticular versus intraarticular prolotherapy on pain and restriction in patients accompanying knee Osteoarthritis (OA).To compare the effect of periarticular against intra-articular prolotherapy on pain and disadvantage in patients accompanying knee OA.Osteoarthritis (OA) is a deteriorating disease that exhibits mainly accompanying painful intersections, articular stiffness, and dropped function. t is often described as a incessant degenerative ailment and thought by many expected an inevitable significance of growing old. This randomized souble blind regulated clinical trial was completed activity at Single-center, university hospital (Imam Hossein Hospital, Tehran, Iran). A total of 104 subjects with never-ending knee OA were enrolled. In the event-articular group, 8 mL of 10% dextrose and 2 mL of 2% lidocaine were introduced. Injections were repeated at 1 and 2 weeks following in position or time the first injection. In the periarticular group, 5 mL of 20% organic compound composed of carbon and 5 mL of 1% lidocaine were injected subcutaneously at 4 points in the periarticular district. Pain and disability, as determined using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), were written at each follow-up visit at 1, 2, 3, 4, and 5 months post-dose. The visual analog scale score was considerably lower in the periarticular compared accompanying the intra-articular group at the 2-, 3-, 4-, and 5-temporal length of event or entity's existence visits but not at 1 month. Morning inflexibility and difficulty in climbing from sitting were revised in both groups and were not considerably different in the periand following-articular groups.Both groups showed improvements in their scores for pain, joint locking, and disadvantage. Pain in both situated and standing positions, difficulty crawling stairs or hiking on flat surfaces, and these symptoms all revised in both groups  from 1 to 5 months subsequently treatment. Periarticular injections about the knee joint burn the inflammatory reaction nearly joint capsule. The infiltration of angering cells and cytokines to the periarticular region may embellish blood perfusion in the capsular joint, increase food to the cartilaginous tissue, and reinforce regeneration.Periarticular prolotherapy has corresponding effects on pain and restriction due to knee OA to following a time-articular injections while avoiding risks of problems.

Author(s) Details:

Zahra Rezasoltani,
Department of Physical Medicine and Rehabilitation, AJA University of Medical Sciences, Tehran, Iran.

Mehrdad Taheri,
Department of Anesthesiology and Pain Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Iran.

Morteza Kazempour Mofrad,
Department of Anesthesiology and Pain Medicine, AJA University of Medical Sciences, Tehran, Iran.

Seyed Amir Mohajerani,
Department of Anesthesiology and Pain Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Iran.

Please see the link here: https://stm.bookpi.org/NAMMS-V7/article/view/11035

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